Roberts M C, Koutsky L A, Holmes K K, LeBlanc D J, Kenny G E
Antimicrob Agents Chemother. 1985 Jul;28(1):141-3. doi: 10.1128/AAC.28.1.141.
Clinical isolates of Mycoplasma hominis resistant to high levels of tetracycline contained DNA sequences homologous to the streptococcal tetracycline determinant, tetM. In contrast, none of the susceptible M. hominis isolates tested carried this determinant. This is the first description of tetM in an unrelated genus and suggests the spread of tetM from Streptococcus spp. to Mycoplasma spp.
对高浓度四环素耐药的人型支原体临床分离株含有与链球菌四环素决定簇tetM同源的DNA序列。相比之下,所检测的敏感人型支原体分离株均未携带该决定簇。这是首次在不相关的属中描述tetM,提示tetM已从链球菌属传播到人型支原体属。