原发性喉小细胞癌。生存时间47个月。病例报告。

Primary small cell carcinoma of the larynx. Survival time of 47 months. Case report.

作者信息

Raposo A, Marco A, García-Solano M E, Martínez-Ortiz M J, García-Purriños F, Lajara J

机构信息

Hospital Universitario Los Arcos del Mar Menor (HULAMM), Torre Octavio Street, San Javier, 30739, Murcia, Spain.

HULAMM, Spain.

出版信息

Ann Med Surg (Lond). 2018 May 9;30:46-49. doi: 10.1016/j.amsu.2018.04.031. eCollection 2018 Jun.

DOI:10.1016/j.amsu.2018.04.031

PMID:29946458

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6016440/

Abstract

Small cell carcinoma (SCC) of the larynx is a rare type of neuroendocrine carcinoma (NEC), few cases of which have been described in the literature. The prognosis for this type of carcinoma is poor, with a survival time typically not exceeding two years. We describe the case of a 54-year-old male patient with a primary tumor in the right ventricular band and a biopsy compatible with SCC. The patient underwent radiotherapy (RT) and concomitant chemotherapy (QT) and, after a relapse at 17 months, underwent total laryngectomy with bilateral neck dissection. The survival time was 47 months. Further studies are required to elucidate the possible causes of the better prognosis in some cases.

摘要

喉小细胞癌（SCC）是一种罕见的神经内分泌癌（NEC），文献中对此类病例的描述较少。这种类型的癌症预后较差，生存时间通常不超过两年。我们描述了一例54岁男性患者，其原发肿瘤位于右室带，活检结果符合SCC。该患者接受了放疗（RT）和同步化疗（QT），在17个月后复发，随后接受了全喉切除术及双侧颈清扫术。生存时间为47个月。需要进一步研究以阐明某些病例预后较好的可能原因。