Mrowczynski Oliver, Mau Christine, Nguyen Dan T, Sarwani Nabeel, Rizk Elias, Harbaugh Kimberly
Department of Neurosurgery, Penn State Hershey Medical Center, Hershey, USA.
Interventional Neuroradiology, Penn State Hershey Medical Center, Hershey, USA.
Cureus. 2018 Apr 25;10(4):e2534. doi: 10.7759/cureus.2534.
Peripheral nerve sheath tumors (PNSTs) may arise sporadically or in the presence of genetic disorders, including neurofibromatosis (NF) types 1 and 2, schwannomatosis, and in patients with large genetic deletions involving the CDKN2A gene. Surgical resection is the treatment of choice for symptomatic PNSTs and offers patients a potential cure; however, pre-existing conditions or tumor location may limit a patient's surgical options. Radiofrequency ablation (RFA) may provide an alternative therapeutic strategy for the treatment of selected PNSTs that are not amenable to surgical resection. Here, we present a case report of a 49-year-old patient with multiple neurofibromas who underwent RFA treatment of two symptomatic retroperitoneal neurofibromas and review previously reported cases of percutaneous treatment of PNSTs.
周围神经鞘瘤（PNSTs）可散发出现，或在存在遗传疾病的情况下发生，这些遗传疾病包括1型和2型神经纤维瘤病（NF）、神经鞘瘤病，以及涉及CDKN2A基因大片段缺失的患者。手术切除是有症状PNSTs的首选治疗方法，可为患者提供潜在的治愈机会；然而，既往存在的疾病或肿瘤位置可能会限制患者的手术选择。射频消融（RFA）可为无法进行手术切除的特定PNSTs提供另一种治疗策略。在此，我们报告一例49岁患有多发性神经纤维瘤的患者，其对两个有症状的腹膜后神经纤维瘤进行了RFA治疗，并回顾了先前报道的经皮治疗PNSTs的病例。
