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儿童肺出血:病因、临床特征及预后。

Pulmonary Hemorrhage in Children: Etiology, Clinical Profile and Outcome.

机构信息

Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, 110029, India.

出版信息

Indian J Pediatr. 2019 Jan;86(1):7-11. doi: 10.1007/s12098-018-2725-x. Epub 2018 Jun 14.

Abstract

OBJECTIVE

To describe etiology, clinical profile, treatment and outcome of children with pulmonary hemorrhage.

METHODS

A chart review of children with pulmonary hemorrhage attending Pediatric Pulmonology services of a tertiary care hospital in North-India was done.

RESULTS

Data of 44 children (mean age 59.2 ± 32.1 mo; 28 boys) were included for the study. Possible idiopathic pulmonary hemosiderosis 16 (36.4%), post infectious complications 11 (25%), immune mediated disorders 8 (18.2%), cardiac and vascular disorders 7 (15.9%), and airway pathologies 2 (4.5%) were the etiologies of pulmonary hemorrhage. Treatment options like medications, bronchial artery embolization and surgical resections were offered according to the etiology. Children with idiopathic pulmonary hemosiderosis and those with immune mediated diseases were treated with systemic steroids and steroid sparing agents; the latter group took longer time to respond and had more relapses.

CONCLUSIONS

Identification of main etiological categories of pulmonary hemorrhage in children could be useful to plan investigations and management of wide range of causes in more practical way.

摘要

目的

描述儿童肺出血的病因、临床特征、治疗方法和转归。

方法

对印度北部一家三级医院儿科肺病科收治的肺出血患儿进行病历回顾。

结果

本研究共纳入 44 例患儿(平均年龄 59.2 ± 32.1 月;男 28 例)。肺含铁血黄素沉着症 16 例(36.4%)、感染后并发症 11 例(25%)、免疫介导性疾病 8 例(18.2%)、心脏和血管疾病 7 例(15.9%)、气道病变 2 例(4.5%)为肺出血的病因。根据病因选择药物治疗、支气管动脉栓塞和手术切除等治疗方案。特发性肺含铁血黄素沉着症和免疫介导性疾病患儿采用全身皮质类固醇和皮质类固醇保留剂治疗;后者组反应时间更长,复发更多。

结论

确定儿童肺出血的主要病因类别有助于更实际地计划广泛病因的检查和管理。

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