Esser J D, Kew M C, Tobias M, Winterton R, Savitch I, Levin J
Clin Nucl Med. 1985 Aug;10(8):586-8. doi: 10.1097/00003072-198508000-00015.
Technetium-99m glucoheptonate (Tc-99m GH) is concentrated in pulmonary and cerebral tumors. The purpose of this study was to assess the uptake of this radionuclide by hepatocellular carcinoma. Its concentration by the primary tumor was compared with that in the non-neoplastic hepatic tissue in 31 patients who showed obvious defects on a colloid scan, and its uptake by pulmonary metastases was examined in six patients with x-ray evidence of this complication. In two patients, the uptake by the tumor was greater than, in six it was equal to, and in ten it was less than that in the non-neoplastic hepatic tissue. In the remaining 13 patients, there was no concentration at all in the tumor. In none of the six patients with multiple pulmonary metastases could uptake of Tc-99m GH by the metastases be demonstrated. It is concluded that Tc-99m GH is of limited value in the diagnosis of primary or metastatic hepatocellular carcinoma.
锝-99m葡庚糖酸盐（Tc-99m GH）可浓聚于肺和脑肿瘤中。本研究的目的是评估这种放射性核素在肝细胞癌中的摄取情况。将31例胶体扫描显示明显缺损患者的原发性肿瘤对其浓聚情况与非肿瘤性肝组织中的情况进行比较，并对6例有肺部转移X线证据的患者检查其肺转移灶对该放射性核素的摄取情况。2例患者肿瘤摄取大于非肿瘤性肝组织，6例患者二者相等，10例患者肿瘤摄取小于非肿瘤性肝组织。其余13例患者肿瘤完全无浓聚。6例有多发肺转移的患者中，均未显示转移灶对Tc-99m GH的摄取。结论是，Tc-99m GH在原发性或转移性肝细胞癌的诊断中价值有限。
