用前列腺特异性膜抗原 PET/CT 和 PET/MRI 成像前列腺癌：当前和未来的应用。
Imaging Prostate Cancer With Prostate-Specific Membrane Antigen PET/CT and PET/MRI: Current and Future Applications.
机构信息
1 Department of Radiology and Biomedical Imaging, University of California, San Francisco, 505 Parnassus Ave, San Francisco, CA 94143-0628.
2 Department of Radiology, San Francisco VA Medical Center, San Francisco, CA.
出版信息
AJR Am J Roentgenol. 2018 Aug;211(2):286-294. doi: 10.2214/AJR.18.19957. Epub 2018 Jun 27.
Abstract
OBJECTIVE
The purpose of this article is to describe the large number of radiotracers being evaluated for prostate-specific membrane antigen (PSMA) PET, which is becoming a central tool in the staging of prostate cancer.
CONCLUSION
PSMA PET is a highly promising modality for the staging of prostate cancer because of its higher detection rate compared with that of conventional imaging. Both PET/CT and PET/MRI offer benefits with PSMA radiotracers, and PSMA PET findings frequently lead to changes in management. It is imperative that subsequent treatment changes be evaluated to show improved outcomes. PSMA PET also has potential applications, including patient selection for PSMA-based radioligand therapy and evaluation of treatment response.
摘要
目的
本文旨在描述大量正在评估的用于前列腺特异性膜抗原（PSMA）PET 的放射性示踪剂，PSMA PET 已成为前列腺癌分期的重要工具。
结论
与传统成像相比，PSMA PET 具有更高的检测率，因此是一种很有前途的前列腺癌分期方法。PSMA 放射性示踪剂的 PET/CT 和 PET/MRI 均具有优势，PSMA PET 的发现常常导致治疗方式的改变。必须评估后续的治疗改变，以显示出更好的结果。PSMA PET 还具有潜在的应用，包括基于 PSMA 的放射性配体治疗的患者选择和治疗反应的评估。
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