Department of Psychiatry, Grup de Recerca en Adiccions Clínic (GRAC), Addictions Unit, Clinical Institute of Neuroscience, Hospital Clínic, Universitat de Barcelona, Red de Trastornos Adictivos (RTA), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
Department of Psychiatry, Grup de Recerca en Adiccions Clínic (GRAC), Addictions Unit, Clinical Institute of Neuroscience, Hospital Clínic, Universitat de Barcelona, Red de Trastornos Adictivos (RTA), Fundació Clínic per la Recerca Biomèdica, Barcelona, Spain.
Eur Addict Res. 2018;24(3):109-117. doi: 10.1159/000488346. Epub 2018 Jun 27.
The Standard Joint Unit (1 SJU = 7 mg of 9-Tetrahydrocannabinol) simplifies the exploration of risky patterns of cannabis use. This study proposes a preliminary quantitative cutoff criterion to screen for cannabis use disorder (CUD).
Socio-demographical data and information on cannabis quantities, frequency of use, and risk for CUD (measured with the Cannabis Abuse Screening Test (CAST) of cannabis users recruited in Barcelona (from February 2015 to June 2016) were collected. CAST scores were categorized into low, moderate, and high risk for CUD, based on the SJU consumed and frequency. Receiver operating characteristic (ROC) analysis related daily SJU with CUD.
Participants (n = 473) were on average 29 years old (SD = 10), men (77.1%), and single (74.6%). With an average of 4 joints per smoking day, 82.5% consumed cannabis almost every day. Risk for CUD (9.40% low, 23.72% moderate, 66.88% high) increased significantly with more frequency and quantities consumed. The ROC analyses suggest 1.2 SJU per day as a cutoff criterion to screen for at least moderate risk for CUD (sensitivity 69.4%, specificity 63.6%).
Frequency and quantity should be considered when exploring cannabis risks. A 1 SJU per day is proposed as a preliminary quantitative-based criterion to screen users with at least a moderate risk for CUD.
标准联合单位（1 SJU = 7 毫克四氢大麻酚）简化了对危险大麻使用模式的探索。本研究提出了一个初步的定量截断标准，用于筛选大麻使用障碍（CUD）。
收集了 2015 年 2 月至 2016 年 6 月在巴塞罗那招募的大麻使用者的社会人口统计学数据以及大麻数量、使用频率和 CUD 风险（使用大麻滥用筛查测试（CAST）测量）信息。根据消耗的 SJU 和频率，将 CAST 评分分为低、中、高 CUD 风险。受试者工作特征（ROC）分析将每日 SJU 与 CUD 相关联。
参与者（n = 473）平均年龄为 29 岁（SD = 10），男性（77.1%），单身（74.6%）。平均每天吸 4 支烟，82.5%的人几乎每天都吸食大麻。CUD 风险（9.40%低、23.72%中、66.88%高）随着吸食频率和数量的增加而显著增加。ROC 分析表明，每天 1.2 SJU 可作为筛选至少中度 CUD 风险的截断标准（敏感性 69.4%，特异性 63.6%）。
在探索大麻风险时应考虑频率和数量。建议每天 1 SJU 作为一个初步的基于定量的标准来筛选至少有中度 CUD 风险的使用者。
