商陆根中的三萜皂苷

[Triterpenoid saponins from roots of Phytolacca acinosa].

作者信息

Du Lin, Wang Jie-Xue, Chen Cong-di, Wang Fang, Zhou Hai-Yun, Du Wei

机构信息

College of Chemistry and Life Science, Chengdu Normal University, Chengdu 611130, China.

Department of Neurosurgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2018 Jun;43(12):2552-2556. doi: 10.19540/j.cnki.cjcmm.20180129.001.

DOI:10.19540/j.cnki.cjcmm.20180129.001

PMID:29950074

Abstract

A new triterpenoid saponin named esculentoside U(1), along with the five known compounds, was isolated and characterized from the roots of Phytolacca acinosa, a commonly used traditional Chinese medicine with anti-inflammatory and anti-rheumatoid activities. The structure of the new saponin was elucidated as 3-O-[β-D-glucopyranosyl-(1→4)]-β-D-xylopyranosyl]-2, 23-dihydroxyolean-11, 13(18)-diene-28, 29-dioic acid 29-methyl ester(1). The assignment of all NMR signals of 1 was performed by means of 2D-NMR experiments.

摘要

从商陆（一种具有抗炎和抗风湿活性的常用传统中药）的根中分离并鉴定出一种名为商陆皂苷U(1)的新三萜皂苷以及五种已知化合物。新皂苷的结构被阐明为3-O-[β-D-吡喃葡萄糖基-(1→4)]-β-D-吡喃木糖基]-2, 23-二羟基齐墩果-11, 13(18)-二烯-28, 29-二酸29-甲酯(1)。通过二维核磁共振实验对1的所有核磁共振信号进行了归属。