Dong Fang-Yan, Cui Guo-He, Zhang Ying-Hua, Zhu Ruo-Nan, Wu Xiu-Juan, Sun Ting-Ting, Wang Wei
Institute of Phytochemistry, Jilin Academy of Chinese Medicine Sciences, Changchun, China.
J Asian Nat Prod Res. 2010 Dec;12(12):1061-8. doi: 10.1080/10286020.2010.533661.
A new triterpenoid saponin, clematomandshurica saponin E, together with four known saponins were isolated and characterized from the roots and rhizomes of Clematis mandshurica (Ranunculaceae), a commonly used traditional Chinese medicine with anti-inflammatory and antirheumatoid activities. On the basis of spectroscopic analysis, including HR-ESI-MS, IR, 1D, and 2D NMR spectral data and hydrolysis followed by chromatographic analysis, the structure of the new triterpenoid saponin was elucidated as 3-O-α-L-rhamnopyranosyl-(1 → 6)-β-D-glucopyranosyl-(1 → 4)-β-D-glucopyranosyl-(1 → 4)-β-D-ribopyranosyl-(1 → 3)-α-L-rhamnopyranosyl-(1 → 2)-α-L-arabinopyranosyl oleanolic acid 28-O-β-D-glucopyranosyl-(1 → 6)-β-D-glucopyranoside.
从毛茛科常用的具有抗炎和抗类风湿活性的传统中药东北铁线莲的根及根茎中分离并鉴定出一种新的三萜皂苷——东北铁线莲皂苷E以及四种已知皂苷。基于高分辨电喷雾电离质谱（HR-ESI-MS）、红外光谱（IR）、一维及二维核磁共振光谱数据等光谱分析，以及水解后进行色谱分析，确定该新三萜皂苷的结构为3-O-α-L-鼠李糖基-(1→6)-β-D-葡萄糖基-(1→4)-β-D-葡萄糖基-(1→4)-β-D-核糖基-(1→3)-α-L-鼠李糖基-(1→2)-α-L-阿拉伯糖基齐墩果酸28-O-β-D-葡萄糖基-(1→6)-β-D-葡萄糖苷。
