Lalwani Ameet Kumar, Faiq Syed Muhammad, Ahuja Jogindar
Department of Radiology, Sindh Institute of Urology and Transplantation (SIUT), Karachi.
J Coll Physicians Surg Pak. 2018 Jul;28(7):564-565. doi: 10.29271/jcpsp.2018.07.564.
Solitary fibrous tumor of kidney is an unusual condition. It is spindle cell tumor with mesenchymal in origin so most commonly reported cases are in pleura, and extra-pleural sites are very rare. It is mostly benign in nature but malignant variant are also reported. Treatment is en bloc resection as in other sites whether pleural or extra-pleural. Prognosis is excellent. This tumor is difficult to diagnose only on imaging features; so for diagnosis, histopathology is needed mostly with immunohistochemical markers like CD34, CD99, Bcl2 proteins. A middle-aged male presented initially with clinical and radiological features, suspected of renal cell carcinoma. Surgery was performed, which proved solitary fibrous tumor on histopathology; and patient on follow-up remained tumor-free till the last follow-up.
肾脏孤立性纤维瘤是一种罕见病症。它是起源于间充质的梭形细胞瘤,因此最常报道的病例发生在胸膜,而胸膜外部位非常罕见。其本质上大多为良性,但也有恶性变体的报道。治疗方法与其他部位(无论是胸膜还是胸膜外)一样,采用整块切除。预后良好。仅依靠影像学特征很难诊断这种肿瘤;因此,诊断大多需要组织病理学检查,并结合免疫组化标志物,如CD34、CD99、Bcl2蛋白。一名中年男性最初表现出临床和放射学特征,怀疑为肾细胞癌。进行了手术,组织病理学检查证实为孤立性纤维瘤;患者在随访期间直至最后一次随访均未复发。