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通过同时使用环氧树脂和聚甲基丙烯酸甲酯软组织等效材料设计和制作两件式甲状腺颈部体模

Design and Production of Two-piece Thyroid-neck Phantom by the Concurrent Use of Epoxy Resin and Poly(methyl methacrylate) Soft Tissue Equivalent Materials.

作者信息

Karimi M, Mostaghimi H, Shams S F, Mehdizadeh A R

机构信息

Department of Biomedical Physics and Engineering, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Advanced Health Technologies Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

J Biomed Phys Eng. 2018 Jun 1;8(2):217-222. eCollection 2018 Jun.

PMID:29951449
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6015643/
Abstract

The aim of this report is to present a new two-piece thyroid-neck phantom produced by the concurrent use of epoxy resin and poly(methyl methacrylate) (PMMA: plexiglass) soft tissue equivalent materials. Accordingly, mass attenuation coefficients of the epoxy resin and the plexiglass compounds were obtained from simulation (NIST XCOM 3.1) and measurements (practical dosimetry) and compared to those related to human soft tissue (ICRU 44). The thyroid-neck phantom and thyroid gland dimensions were derived from scientific references and the atlas of human anatomy, respectively. The thyroid phantom was designed by CATIA V5R16 software and produced by the epoxy resin compound by three-dimensional printer. Other organs were designed by ProNest software and made by the plexiglass sheets by CNC laser cutting machine. The mass attenuation coefficients for the epoxy resin (50 keV- 20 MeV) and the plexiglass (0-20 MeV) were comparable to human soft tissue (ICRU 44), all with standard relative deviation beneath 5%. In addition, the SPECT images indicated the similarity between human thyroid tissue and its phantom. In conclusion, this study proves the feasibility and reliability of epoxy resin application in the production of two-piece thyroid-neck phantom. This phantom can be applied in the calibration of gamma camera systems, dosimetry and gamma spectrometry in the nuclear medicine field.

摘要

本报告旨在介绍一种通过同时使用环氧树脂和聚甲基丙烯酸甲酯（PMMA：有机玻璃）软组织等效材料制成的新型两件式甲状腺颈部体模。据此，从模拟（NIST XCOM 3.1）和测量（实际剂量测定）中获得了环氧树脂和有机玻璃化合物的质量衰减系数，并与那些与人体软组织相关的系数（ICRU 44）进行了比较。甲状腺颈部体模和甲状腺的尺寸分别源自科学参考文献和人体解剖图谱。甲状腺体模由CATIA V5R16软件设计，并通过三维打印机用环氧树脂化合物制作而成。其他器官由ProNest软件设计，并通过CNC激光切割机用有机玻璃板制作而成。环氧树脂（50 keV - 20 MeV）和有机玻璃（0 - 20 MeV）的质量衰减系数与人体软组织（ICRU 44）相当，所有标准相对偏差均低于5%。此外，SPECT图像显示了人体甲状腺组织与其体模之间的相似性。总之，本研究证明了环氧树脂在制作两件式甲状腺颈部体模中的可行性和可靠性。这种体模可应用于核医学领域伽马相机系统的校准、剂量测定和伽马能谱分析。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/378b/6015643/ebd7335042f6/JBPE-8-217-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/378b/6015643/18678fbfeca3/JBPE-8-217-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/378b/6015643/870a39afaf4c/JBPE-8-217-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/378b/6015643/8cbee46fc60c/JBPE-8-217-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/378b/6015643/9a8cfc80791c/JBPE-8-217-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/378b/6015643/ce53a0e6a250/JBPE-8-217-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/378b/6015643/9c0fb8428648/JBPE-8-217-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/378b/6015643/9e6be18781cb/JBPE-8-217-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/378b/6015643/ebd7335042f6/JBPE-8-217-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/378b/6015643/18678fbfeca3/JBPE-8-217-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/378b/6015643/870a39afaf4c/JBPE-8-217-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/378b/6015643/8cbee46fc60c/JBPE-8-217-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/378b/6015643/9a8cfc80791c/JBPE-8-217-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/378b/6015643/ce53a0e6a250/JBPE-8-217-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/378b/6015643/9c0fb8428648/JBPE-8-217-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/378b/6015643/9e6be18781cb/JBPE-8-217-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/378b/6015643/ebd7335042f6/JBPE-8-217-g008.jpg

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