Krieghoff-Henning Eva, Folkerts Juliane, Penzkofer Andrea, Weg-Remers Susanne
Med Monatsschr Pharm. 2017 Feb;40(2):48-54.
Cancer is characterized by proliferation of cells that have managed to evade central endogenous control mechanisms. Cancers are grouped according to their organ or tissue of origin, but increasingly also based on molecular characteristics of the respective cancer cells. Due to the rapid technological advances of the last years, it is now possible to analyze the molecular makeup of different cancer types in detail within short time periods. The accumulating knowledge about development and progression of cancer can be used to develop more precise diagnostics and more effective and/or less toxic cancer therapies. In the long run, the goal is to offer to every cancer patient a therapeutic regimen that is tailored to his individual disease and situation in an optimal way.
癌症的特征是细胞增殖，这些细胞成功逃避了内源性中央控制机制。癌症根据其起源的器官或组织进行分类，但越来越多地也基于相应癌细胞的分子特征进行分类。由于过去几年技术的快速进步，现在有可能在短时间内详细分析不同癌症类型的分子组成。关于癌症发生和发展积累的知识可用于开发更精确的诊断方法以及更有效和/或毒性更小的癌症治疗方法。从长远来看，目标是为每位癌症患者提供一种以最佳方式根据其个体疾病和情况量身定制的治疗方案。
