Yancey Russell
PGY-2 Resident, New York University-Langone Hospital Dental Anesthesiology Service, Brooklyn, New York.
Anesth Prog. 2018 Summer;65(2):131-138. doi: 10.2344/anpr-65-02-12.
Hypertension is an important health challenge that affects millions of people across the world and is a major risk factor for cardiovascular disease. It is critical that anesthesia providers have a working knowledge of the systemic implications of hypertension. This review article will discuss the medical definitions of hypertension, the physiology of maintaining blood pressure, outpatient treatment of hypertension, anesthetic implications, and the common medications used by anesthesia providers in the treatment of hypertension. Part I will provide an overview of hypertension and blood pressure regulation. In addition, drugs affecting predominantly renal control of hypertension, such as diuretics, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, and renin-inhibiting agents, will be discussed. In part II, the remaining major antihypertensive medications will be reviewed as well as anesthetic implications of managing patients with hypertension.
高血压是一项重大的健康挑战,影响着全球数百万人,并且是心血管疾病的主要危险因素。麻醉医生掌握高血压对全身影响的实用知识至关重要。这篇综述文章将讨论高血压的医学定义、维持血压的生理学、高血压的门诊治疗、麻醉相关问题以及麻醉医生治疗高血压常用的药物。第一部分将概述高血压和血压调节。此外,还将讨论主要影响肾脏对高血压控制的药物,如利尿剂、血管紧张素转换酶抑制剂、血管紧张素受体阻滞剂和肾素抑制剂。在第二部分中,将回顾其余主要的抗高血压药物以及管理高血压患者的麻醉相关问题。