血管紧张素转换酶抑制剂所致血管性水肿。
ACE inhibitor-induced angioedema.
机构信息
Department of Medicine, Penn State University, Hershey, PA 17033, USA.
出版信息
Curr Allergy Asthma Rep. 2012 Feb;12(1):72-8. doi: 10.1007/s11882-011-0238-z.
Much has been written about hereditary angioedema (HAE) in recent literature; however, the prevalence of angiotensin-converting enzyme inhibitor-induced angioedema (ACEiIA) far exceeds that of HAE. Similarly, multiple therapies have been developed for HAE, yet no definitive therapy is available for ACEiIA. In this article, we discuss the mechanism, prevalence, pathophysiology, and management of ACEiIA, with focus on newer therapies recently approved for HAE and how they may be effective for ACEiIA.
最近的文献中已经有很多关于遗传性血管水肿（HAE）的报道；然而，血管紧张素转换酶抑制剂诱导的血管水肿（ACEiIA）的患病率远远超过 HAE。同样，已经开发出多种治疗 HAE 的方法，但 ACEiIA 仍没有明确的治疗方法。本文讨论了 ACEiIA 的机制、患病率、病理生理学和管理，重点介绍了最近批准用于 HAE 的新疗法以及它们如何对 ACEiIA 有效。
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