消除UDP葡萄糖焦磷酸化酶的突变对胡萝卜软腐欧文氏菌胡萝卜软腐亚种致病性的影响。
Effects of a mutation that eliminates UDP glucose-pyrophosphorylase on the pathogenicity of Erwinia carotovora subsp. carotovora.
作者信息
Jayaswal R K, Bressan R A, Handa A K
出版信息
J Bacteriol. 1985 Oct;164(1):473-6. doi: 10.1128/jb.164.1.473-476.1985.
Abstract
A nonpathogenic mutant of Erwinia carotovora obtained by Mu d1 mutagenesis was defective in the ability to utilize several carbon sources. The basis of the mutation was analyzed biochemically and shown to be a defect in the ability to form UDP glucose-pyrophosphorylase. The nonpathogenic phenotype of the mutant was caused by its sensitivity to galactose.
摘要
通过Mu d1诱变获得的胡萝卜软腐欧文氏菌非致病性突变体在利用多种碳源的能力上存在缺陷。通过生化分析确定了突变的基础，结果表明是形成UDP葡萄糖焦磷酸化酶的能力存在缺陷。该突变体的非致病表型是由其对半乳糖的敏感性引起的。
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