早发型败血症的二级预防：一种针对有风险新生儿的具有侵袭性更小的意大利式管理方法。
Secondary prevention of early-onset sepsis: a less invasive Italian approach for managing neonates at risk.
机构信息
Unità Operativa di Terapia Intensiva Neonatale, Dipartimento Integrato Materno-Infantile, Azienda Ospedaliero-Universitaria Policlinico, Modena, Italy.
Scuola di specializzazione in Pediatria, Università di Modena e Reggio Emilia, Azienda Ospedaliero-Universitaria Policlinico, Via del Pozzo, 71 -, 41124, Modena, MO, Italy.
出版信息
Ital J Pediatr. 2018 Jun 28;44(1):73. doi: 10.1186/s13052-018-0515-8.
Abstract
Strategies to prevent early-onset sepsis (EOS) have led to a substantial decline in many countries. However, one of the most controversial topics in neonatology is the management of asymptomatic full-term and late preterm neonates at risk for EOS, and guidelines lack substantial consensus regarding this issue. A strategy for managing neonates, entirely based on serial physical examinations, has been developed in two Italian regions. This strategy seems safe, while reducing laboratory tests and unnecessary antibiotics. In the current commentary we provide area-based data concerning the prevention of EOS in 2 northern Italian regions, and we detail the results of their strategy for managing healthy-appearing newborns at risk for EOS.
摘要
预防早发性败血症（EOS）的策略已在许多国家取得显著成效。然而，新生儿学中最具争议的话题之一是管理无症状的足月和晚期早产儿的 EOS 风险，并且在这个问题上，指南缺乏实质性的共识。意大利的两个地区已经制定了一种完全基于定期体格检查的管理新生儿的策略。该策略似乎是安全的，同时减少了实验室检查和不必要的抗生素使用。在当前的评论中，我们提供了意大利北部两个地区预防 EOS 的基于区域的数据，并详细介绍了他们管理有 EOS 风险的外观健康新生儿的策略的结果。
相似文献
1
Secondary prevention of early-onset sepsis: a less invasive Italian approach for managing neonates at risk.早发型败血症的二级预防：一种针对有风险新生儿的具有侵袭性更小的意大利式管理方法。
Ital J Pediatr. 2018 Jun 28;44(1):73. doi: 10.1186/s13052-018-0515-8.
2
Group B Streptococcus early-onset disease and observation of well-appearing newborns.B 族链球菌早发型疾病与外观正常新生儿的观察。
PLoS One. 2019 Mar 20;14(3):e0212784. doi: 10.1371/journal.pone.0212784. eCollection 2019.
3
Strategies for preventing early-onset sepsis and for managing neonates at-risk: wide variability across six Western countries.
J Matern Fetal Neonatal Med. 2019 Sep;32(18):3102-3108. doi: 10.1080/14767058.2018.1454423. Epub 2018 Apr 1.
4
The capture rate of at-risk term newborns for early-onset group B streptococcal sepsis determined by a risk factor approach.通过风险因素法确定的早发型B族链球菌败血症高危足月儿的捕获率。
Am J Obstet Gynecol. 1999 Nov;181(5 Pt 1):1243-9. doi: 10.1016/s0002-9378(99)70116-x.
5
Prevention of perinatal group B streptococcal disease--revised guidelines from CDC, 2010.预防围产期 B 型链球菌病——美国疾病预防控制中心 2010 年修订指南。
MMWR Recomm Rep. 2010 Nov 19;59(RR-10):1-36.
6
Routine culture-based screening versus risk-based management for the prevention of early-onset group B streptococcus disease in the neonate: a systematic review.基于常规培养的筛查与基于风险的管理在预防新生儿早发型B族链球菌病中的比较：一项系统评价
JBI Database System Rev Implement Rep. 2015 Apr 17;13(3):206-46. doi: 10.11124/jbisrir-2015-1876.
7
Management of well appearing infants born to afebrile mothers with inadequate GBS prophylaxis: A retrospective comparison of the three approaches recommended by the COFN.无热型产妇产程中出现的外观正常的婴儿，GBS 预防措施不充分时的处理：COFN 推荐的三种方法的回顾性比较。
J Neonatal Perinatal Med. 2022;15(2):297-302. doi: 10.3233/NPM-210798.
8
Incidence of fever in labor and risk of neonatal sepsis.分娩时发热的发生率与新生儿脓毒症的风险。
Am J Obstet Gynecol. 2017 Jun;216(6):596.e1-596.e5. doi: 10.1016/j.ajog.2017.02.022. Epub 2017 Feb 16.
9
Brief comments on three existing approaches for managing neonates at risk of early-onset sepsis.简要评论三种现有方法在管理有早发性败血症风险的新生儿方面的应用。
Ital J Pediatr. 2021 Jul 18;47(1):159. doi: 10.1186/s13052-021-01107-3.
10
Strategies for preventing group B streptococcal infections in newborns: a nation-wide survey of Italian policies.预防新生儿 B 群链球菌感染的策略：意大利全国政策调查。
Ital J Pediatr. 2017 Nov 2;43(1):98. doi: 10.1186/s13052-017-0409-1.
引用本文的文献
1
Management of neonates at risk of early onset sepsis: a probability-based approach and recent literature appraisal : Update of the Swiss national guideline of the Swiss Society of Neonatology and the Pediatric Infectious Disease Group Switzerland.管理有早发性败血症风险的新生儿：基于概率的方法和最新文献评估：瑞士新生儿学会和瑞士儿科传染病学会国家指南的更新。
Eur J Pediatr. 2024 Dec;183(12):5517-5529. doi: 10.1007/s00431-024-05811-0. Epub 2024 Oct 17.
2
Neonatal Early Onset Sepsis (EOS) Calculator plus Universal Serial Physical Examination (SPE): A Prospective Two-Step Implementation of a Neonatal EOS Prevention Protocol for Reduction of Sepsis Workup and Antibiotic Treatment.新生儿早发型败血症（EOS）计算器加通用串行体格检查（SPE）：一项前瞻性两步实施的新生儿EOS预防方案，以减少败血症检查和抗生素治疗。
Antibiotics (Basel). 2022 Aug 11;11(8):1089. doi: 10.3390/antibiotics11081089.
3
Characterization of Neonatal Infections by Gram-Negative Bacilli and Associated Risk Factors, Havana, Cuba.古巴哈瓦那革兰氏阴性杆菌所致新生儿感染的特征及相关危险因素
Infect Dis Rep. 2021 Mar 9;13(1):219-229. doi: 10.3390/idr13010025.
4
Neonate Bloodstream Infections in Organization for Economic Cooperation and Development Countries: An Update on Epidemiology and Prevention.经济合作与发展组织国家的新生儿血流感染：流行病学与预防的最新情况
J Clin Med. 2019 Oct 21;8(10):1750. doi: 10.3390/jcm8101750.
本文引用的文献
1
What's the harm? Risks and benefits of evolving rule-out sepsis practices.有何危害？排除脓毒症实践演变的风险与获益。
J Perinatol. 2018 Jun;38(6):614-622. doi: 10.1038/s41372-018-0081-3. Epub 2018 Feb 26.
2
Strategies for preventing group B streptococcal infections in newborns: a nation-wide survey of Italian policies.预防新生儿 B 群链球菌感染的策略：意大利全国政策调查。
Ital J Pediatr. 2017 Nov 2;43(1):98. doi: 10.1186/s13052-017-0409-1.
3
Prevention of Early-onset Neonatal Group B Streptococcal Disease: Green-top Guideline No. 36.早发型新生儿B族链球菌病的预防：第36号绿皮书指南
BJOG. 2017 Nov;124(12):e280-e305. doi: 10.1111/1471-0528.14821. Epub 2017 Sep 13.
4
Serial physical examinations, a simple and reliable tool for managing neonates at risk for early-onset sepsis.连续体格检查，是管理有早发性败血症风险新生儿的一种简单且可靠的工具。
World J Clin Pediatr. 2016 Nov 8;5(4):358-364. doi: 10.5409/wjcp.v5.i4.358.
5
An area-based study on intrapartum antibiotic prophylaxis for preventing group B streptococcus early-onset disease: advances and limitations.一项关于产时抗生素预防以预防B族链球菌早发型疾病的基于区域的研究：进展与局限
J Matern Fetal Neonatal Med. 2017 Jul;30(14):1739-1744. doi: 10.1080/14767058.2016.1224832. Epub 2016 Sep 5.
6
Variation in Current Management of Term and Late-preterm Neonates at Risk for Early-onset Sepsis: An International Survey and Review of Guidelines.足月儿和晚期早产儿早发型败血症风险当前管理的差异：一项国际调查及指南综述
Pediatr Infect Dis J. 2016 May;35(5):494-500. doi: 10.1097/INF.0000000000001063.
7
The burden of early-onset sepsis in Emilia-Romagna (Italy): a 4-year, population-based study.意大利艾米利亚-罗马涅地区早发性败血症的负担：一项基于人群的4年研究。
J Matern Fetal Neonatal Med. 2016 Oct;29(19):3126-31. doi: 10.3109/14767058.2015.1114093. Epub 2016 Jan 14.
8
Antimicrobial therapy in neonatal intensive care unit.新生儿重症监护病房的抗菌治疗
Ital J Pediatr. 2015 Apr 1;41:27. doi: 10.1186/s13052-015-0117-7.
9
Reappraisal of guidelines for management of neonates with suspected early-onset sepsis.对疑似早发型败血症新生儿管理指南的重新评估。
J Pediatr. 2015 Apr;166(4):1070-4. doi: 10.1016/j.jpeds.2014.12.023. Epub 2015 Jan 29.
10
Safety of physical examination alone for managing well-appearing neonates ≥ 35 weeks' gestation at risk for early-onset sepsis.仅通过体格检查管理孕龄≥35周、外表良好但有早发性败血症风险的新生儿的安全性。
J Matern Fetal Neonatal Med. 2015 Jul;28(10):1123-7. doi: 10.3109/14767058.2014.946499. Epub 2014 Sep 10.
Zotero 插件