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巴西第二个月痰涂片作为结核病治疗结果的预测指标

Second month sputum smear as a predictor of tuberculosis treatment outcomes in Brazil.

作者信息

do Socorro Nantua Evangelista Maria, Maia Rosalia, Toledo João Paulo, de Abreu Ricardo Gadelha, Braga José Uereles, Barreira Draurio, Trajman Anete

机构信息

Brazil, Ministry of Health, National Tuberculosis Program, Federal District, Brasília, Brazil.

University of Brasilia (UnB), Federal District, Brasília, Brazil.

出版信息

BMC Res Notes. 2018 Jun 28;11(1):414. doi: 10.1186/s13104-018-3522-3.

DOI:10.1186/s13104-018-3522-3
PMID:29954436
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6022340/
Abstract

OBJECTIVE

The value of sputum smear microscopy (SSM) after 2 months of treatment in the management of pulmonary tuberculosis is controversial. We analysed second month-SSM conversion as a predictor of treatment success in Brazil.

RESULTS

Overall successful outcome rate was 89.4%. The predictive value of second month-SSM conversion for successful outcomes was 85.2% 72,479/85,118), while the predictive value of non-conversion for unfavourable outcomes was 26.9% (2712/10,071). Unfavourable treatment outcomes were twice more likely among patients who did not convert (adjusted OR = 2.06; 1.97-2.16).

摘要

目的

治疗2个月后的痰涂片显微镜检查（SSM）在肺结核管理中的价值存在争议。我们分析了巴西第二个月痰涂片显微镜检查转阴情况作为治疗成功的预测指标。

结果

总体成功结局率为89.4%。第二个月痰涂片显微镜检查转阴对成功结局的预测价值为85.2%（72479/85118），而未转阴对不良结局的预测价值为26.9%（2712/10071）。未转阴的患者出现不良治疗结局的可能性是转阴患者的两倍（调整后的比值比=2.06；1.97 - 2.16）。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ccd/6022340/47853ed889c5/13104_2018_3522_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ccd/6022340/47853ed889c5/13104_2018_3522_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ccd/6022340/47853ed889c5/13104_2018_3522_Fig1_HTML.jpg

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