动脉粥样硬化作为自身免疫性疾病。
Atherosclerosis as autoimmune disease.
作者信息
Sima Petr, Vannucci Luca, Vetvicka Vaclav
机构信息
Institute of Microbiology, Laboratory of Immunotherapy, Prague, Czech.
University of Louisville, Department of Pathology, Louisville, KY, USA.
出版信息
Ann Transl Med. 2018 Apr;6(7):116. doi: 10.21037/atm.2018.02.02.
Abstract
No attention is usually focused on the possible involvement of immune mechanisms, particularly of autoimmunity, on the development and progress of atherosclerosis. The pioneering work occurring almost 50 years ago was overlooked, and the idea of atherosclerosis as an autoimmune disease only started gaining traction about 10 years ago. Our review discusses the recent findings and offers insights into the possibility that alterations of the immune system play a significant role in the development of atherosclerosis.
摘要
通常没有人关注免疫机制，尤其是自身免疫，在动脉粥样硬化发生和发展过程中可能起到的作用。近50年前的开创性工作被忽视了，而动脉粥样硬化是一种自身免疫性疾病的观点直到大约10年前才开始受到关注。我们的综述讨论了最近的研究发现，并深入探讨了免疫系统的改变在动脉粥样硬化发展中起重要作用的可能性。
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Artery Tertiary Lymphoid Organs: Powerhouses of Atherosclerosis Immunity.
Front Immunol. 2016 Oct 10;7:387. doi: 10.3389/fimmu.2016.00387. eCollection 2016.
2
Artery Tertiary Lymphoid Organs Control Multilayered Territorialized Atherosclerosis B-Cell Responses in Aged ApoE-/- Mice.
Arterioscler Thromb Vasc Biol. 2016 Jun;36(6):1174-85. doi: 10.1161/ATVBAHA.115.306983. Epub 2016 Apr 21.
3
Artery Tertiary Lymphoid Organs Control Aorta Immunity and Protect against Atherosclerosis via Vascular Smooth Muscle Cell Lymphotoxin β Receptors.
Immunity. 2015 Jun 16;42(6):1100-15. doi: 10.1016/j.immuni.2015.05.015.
4
Atherosclerosis and the role of immune cells.
World J Clin Cases. 2015 Apr 16;3(4):345-52. doi: 10.12998/wjcc.v3.i4.345.
5
Artery tertiary lymphoid organs contribute to innate and adaptive immune responses in advanced mouse atherosclerosis.
Circ Res. 2014 May 23;114(11):1772-87. doi: 10.1161/CIRCRESAHA.114.301137.
6
Innate immunity and monocyte-macrophage activation in atherosclerosis.
J Inflamm (Lond). 2011 Apr 28;8:9. doi: 10.1186/1476-9255-8-9.
7
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.
Nature. 2010 Apr 29;464(7293):1357-61. doi: 10.1038/nature08938.
8
Adaptive immunity and atherosclerosis.
Clin Immunol. 2010 Jan;134(1):33-46. doi: 10.1016/j.clim.2009.07.002. Epub 2009 Jul 26.
9
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Arthritis Res Ther. 2009;11(2):217. doi: 10.1186/ar2631. Epub 2009 Apr 3.
10
The inflammasomes: guardians of the body.
Annu Rev Immunol. 2009;27:229-65. doi: 10.1146/annurev.immunol.021908.132715.
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