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《多发性硬化症下尿路功能障碍的管理》。

The Management of Lower Urinary Tract Dysfunction in Multiple Sclerosis.

机构信息

Department of Uro-Neurology, The National Hospital For Neurology and Neurosurgery and UCL Institute for Neurology, Queen Square, London, WC1N 3BG, UK.

出版信息

Curr Neurol Neurosci Rep. 2018 Jun 28;18(8):54. doi: 10.1007/s11910-018-0857-z.

Abstract

PURPOSE OF REVIEW

Multiple sclerosis (MS) is the most frequent neuroinflammatory disease of the central nervous system and is commonly associated with lower urinary tract (LUT) dysfunction. As a consequence, health-related quality of life is often impaired and the upper urinary tract might be at risk for damage. The aim of this review is to give an overview of current treatment options for LUT dysfunction in patients with MS.

RECENT FINDINGS

The treatment is tailored to the type of dysfunction-storage or voiding dysfunction-beginning with conservative treatment options and ending with invasive therapies and surgery. Additionally, alternative options, e.g., different intravesical therapies or cannabinoids, have been evaluated in recent years with promising results. Current available therapies offer different possible treatments for LUT dysfunction in patients with MS. They address either voiding or storage dysfunction and therefore ameliorate LUT symptoms improve quality of life and protect the upper urinary tract.

摘要

目的综述

多发性硬化症(MS)是中枢神经系统最常见的神经炎症性疾病,常伴有下尿路(LUT)功能障碍。因此,患者的健康相关生活质量常常受损,而上尿路可能有受损的风险。本篇综述旨在介绍目前针对 MS 患者 LUT 功能障碍的治疗选择。

最新发现

治疗方案根据功能障碍的类型(储尿或排尿功能障碍)进行定制,从保守治疗开始,最后采用侵入性治疗和手术。此外,近年来还评估了替代方案,例如不同的膀胱内治疗或大麻素,取得了有前景的结果。目前可用的治疗方法为 MS 患者的 LUT 功能障碍提供了不同的治疗选择。它们针对排尿或储尿功能障碍,因此改善 LUT 症状、提高生活质量并保护上尿路。

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