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联合团体习惯逆转训练和暴露反应预防与个体训练比较:一项随机对照临床试验。

Combined habit reversal training and exposure response prevention in a group setting compared to individual training: a randomized controlled clinical trial.

机构信息

Center for Child and Adolescent Psychiatry, Aarhus University Hospital Risskov, Risskov, Denmark.

Institute of Clinical Medicine, Health, Aarhus University, Aarhus, Denmark.

出版信息

Eur Child Adolesc Psychiatry. 2019 Jan;28(1):57-68. doi: 10.1007/s00787-018-1187-z. Epub 2018 Jun 28.

Abstract

Chronic tic disorders may have a huge influence on quality of life. Habit reversal training (HRT) and exposure response prevention (ERP) are effective treatments. In a blinded assessed, open trial, this study evaluates the effectiveness of a newly developed Scandinavian tic treating manual designed to treat adolescents with a chronic tic disorder, combining HRT and ERP. The study compared the efficacy of treatment based on the same manual delivered either individually or in groups. The study was an open randomized controlled clinical trial in which adolescents were randomized to either individual or group therapy. Both therapies included nine sessions. The parents were offered group-based psycho-education. The exclusion criteria were chosen to design a study that would be close to clinical practice. This is the first Scandinavian study that examines the effectiveness of a treatment manual combining HRT and ERP delivered in an individual and group setting. The study showed a significant reduction of the Total Tic score on the Yale Global Tic Severity Scale both in the individual (effect size 1.21) and group setting (effect size 1.38). A total of 66.7% of participants were considered responders. There was no statistical significant difference between the individual and group setting apart from the functional impairment score. The reductions were comparable with those shown in other studies. The participants applied both HRT and ERP, and the majority (36/59) reported an increased post-treatment experience of control. The newly designed Scandinavian manual was equally effective in the individual and group setting with effect sizes comparable with those shown in other studies.

摘要

慢性抽动障碍可能会对生活质量产生巨大影响。习惯逆转训练(HRT)和暴露反应预防(ERP)是有效的治疗方法。在一项盲法评估、开放性试验中,本研究评估了一种新开发的斯堪的纳维亚抽动治疗手册的有效性,该手册旨在治疗患有慢性抽动障碍的青少年,结合 HRT 和 ERP。该研究比较了基于相同手册的个体治疗和小组治疗的疗效。该研究是一项开放的随机对照临床试验,其中青少年被随机分配到个体或小组治疗。两种疗法均包括九次治疗。父母接受了基于小组的心理教育。选择排除标准是为了设计一项接近临床实践的研究。这是第一项检查结合 HRT 和 ERP 的治疗手册在个体和小组环境中的有效性的斯堪的纳维亚研究。研究显示,在耶鲁全球抽动严重程度量表上,个体(效应大小 1.21)和小组(效应大小 1.38)治疗后总抽动评分均显著降低。共有 66.7%的参与者被认为是有反应者。除了功能障碍评分外,个体和小组治疗之间没有统计学上的显著差异。减少幅度与其他研究中显示的相似。参与者应用了 HRT 和 ERP,大多数(36/59)报告治疗后控制感增强。新设计的斯堪的纳维亚手册在个体和小组治疗中同样有效,其效果大小与其他研究中显示的相似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b003/6349803/f4e0e2a0d247/787_2018_1187_Fig1_HTML.jpg

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