Wang Yan-Zhen, Zhang Xi, Han Xin-Min
Department of Rehabilitation, Children's Hospital of Shanxi, Taiyuan 030012, Shanxi Province, China.
Department of Pediatrics, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210029, Jiangsu Province, China.
World J Psychiatry. 2024 Jul 19;14(7):999-1008. doi: 10.5498/wjp.v14.i7.999.
Cognitive-behavioral therapy (CBT) and habit reversal training (HRT) have shown application potential in addressing tic symptoms and comorbid psychiatric conditions. Despite their theoretical potential, empirical evidence on their combined efficacy remains limited.
To evaluate the efficacy of CBT combined with HRT on anxiety disorders in children with Tourette's syndrome (TS).
Clinical data of children with TS admitted to our hospital from January 2022 to June 2023 were collected, and the patients were grouped into the conventional therapy (control) group and the CBT combined with HRT group. Baseline characteristics, anxiety scores, tic severity scores, treatment adherence, and parental satisfaction were assessed. Statistical analysis was performed using t-tests, chi-square tests, and correlation analysis.
A total of 136 patients, including 65 patients in the control group and 71 patients in the CBT combined with HRT group, were included. The CBT combined with HRT group showed remarkable improvements compared with the control group. Post-intervention assessment revealed a decrease in anxiety scores from 63.52 ± 1.81 to 40.53 ± 1.64 ( = 2.022, = 0.045), and the Yale Global Tic Severity Scale total score decreased from 22.14 ± 5.67 to 16.28 ± 4.91 ( = 2.288, = 0.024). Treatment adherence was significantly higher in the CBT combined with HRT group (85.47 ± 7.62%) compared with the control group (82.32 ± 6.54%; = 2.596, = 0.010). Parental satisfaction scores were also higher in the CBT combined with HRT group (8.69 ± 1.77) compared with the control group (7.87 ± 1.92; = 2.592, = 0.011).
This study demonstrates that CBT combined with HRT significantly reduces anxiety symptoms and tic severity in children with TS, with higher treatment adherence and parental satisfaction. These findings support the potential application of this comprehensive therapeutic approach for TS treatment.
认知行为疗法（CBT）和习惯逆转训练（HRT）在解决抽动症状和共病精神疾病方面已显示出应用潜力。尽管它们具有理论潜力，但关于其联合疗效的实证证据仍然有限。
评估CBT联合HRT对 Tourette 综合征（TS）患儿焦虑症的疗效。
收集 2022 年 1 月至 2023 年 6 月我院收治的 TS 患儿的临床资料，将患者分为传统治疗（对照）组和 CBT 联合 HRT 组。评估基线特征、焦虑评分、抽动严重程度评分、治疗依从性和家长满意度。采用 t 检验、卡方检验和相关性分析进行统计分析。
共纳入 136 例患者，其中对照组 65 例，CBT 联合 HRT 组 71 例。与对照组相比，CBT 联合 HRT 组有显著改善。干预后评估显示焦虑评分从 63.52±1.81 降至 40.53±1.64（t = 2.022，P = 0.045），耶鲁全球抽动严重程度量表总分从 22.14±5.67 降至 16.28±4.91（t = 2.288，P = 0.024）。CBT 联合 HRT 组的治疗依从性（85.47±7.62%）显著高于对照组（82.32±6.54%；t = 2.596，P = 0.010）。CBT 联合 HRT 组的家长满意度评分（8.69±1.77）也高于对照组（7.87±1.92；t = 2.592，P = 0.011）。
本研究表明，CBT 联合 HRT 可显著降低 TS 患儿的焦虑症状和抽动严重程度，治疗依从性和家长满意度更高。这些发现支持了这种综合治疗方法在 TS 治疗中的潜在应用。
