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一只婴儿大猩猩(西部低地大猩猩)的内脏利什曼病:临床症状、诊断及单剂量脂质体两性霉素B治疗成功

Visceral leishmaniasis in an infant gorilla (Gorilla gorilla gorilla): Clinical signs, diagnosis, and successful treatment with single-dose liposomal amphotericin B.

作者信息

Tinoco Herlandes Penha, da Costa Maria Elvira Loyola Teixeira, Pessanha Angela Tinoco, Coelho Carlyle Mendes, de Carvalho Tatiane Furtado, Mol Juliana Pinto da Silva, Viana Agostinho Gonçalves, Bueno Lilian Lacerda, Fujiwara Ricardo Toshio, Santos Renato Lima

机构信息

Departamento de Jardim Zoológico, Fundação Zoo-Botânica de Belo Horizonte, Belo Horizonte, Brazil.

Departamento de Clínica e Cirurgia Veterinárias, Escola de Veterinária, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.

出版信息

J Med Primatol. 2018 Dec;47(6):416-418. doi: 10.1111/jmp.12354. Epub 2018 Jun 29.

Abstract

A 2-year-old captive gorilla (Gorilla gorilla gorilla) was diagnosed with visceral leishmaniasis in Brazil, and treated with a single dose of liposomal amphotericin B, which resulted in clinical cure. This is the first report of visceral leishmaniasis in gorillas, and the first reported liposomal amphotericin B treatment in great apes.

摘要

在巴西,一只2岁的圈养大猩猩(西部低地大猩猩)被诊断出患有内脏利什曼病,用单剂量的脂质体两性霉素B进行治疗后实现了临床治愈。这是大猩猩内脏利什曼病的首例报告,也是首次报道在大猩猩中使用脂质体两性霉素B进行治疗。

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