Masaryk University, Faculty of Science, RECETOX, Kamenice 5, 625 00, Brno, Czech Republic.
Masaryk University, Faculty of Science, RECETOX, Kamenice 5, 625 00, Brno, Czech Republic.
Chemosphere. 2018 Oct;209:568-577. doi: 10.1016/j.chemosphere.2018.06.102. Epub 2018 Jun 15.
Impacts of neonicotinoids on non-target insects, including aquatic species, may significantly influence ecosystem structure and functioning. The present study investigated the sensitivity of Chironomus riparius to imidacloprid exposures during 24-h, 10- and 28-days by assessing larval survival, growth, emergence and oxidative stress-related parameters. C. riparius exhibited high sensitivity compared to other model aquatic species with acute 24-h LC being 31.5 μg/L and 10-days LOEC (growth) 0.625 μg/L. A 28-days partial life cycle test demonstrated imidacloprid effects on the emergence of C. riparius. Exposure to sublethal concentrations during 10-days caused an imbalance in the reduced and oxidized glutathione (GSH and GSSG), and slightly induced lipid peroxidation (increased malondialdehyde, MDA). Our results indicate that oxidative stress may be a relevant mechanism in the neonicotinoid toxicity, reflected in the insect development and life cycle parameters.
新烟碱类杀虫剂对非靶标昆虫（包括水生生物）的影响可能会显著影响生态系统的结构和功能。本研究通过评估幼虫的存活率、生长、变态和氧化应激相关参数，调查了摇蚊在 24 小时、10 天和 28 天暴露于吡虫啉中的敏感性。与其他模式水生生物相比，摇蚊表现出较高的敏感性，急性 24 小时 LC50 为 31.5μg/L，10 天 LOEC（生长）为 0.625μg/L。28 天部分生命周期试验表明，吡虫啉对摇蚊的变态有影响。在 10 天的亚致死浓度暴露下，导致还原型和氧化型谷胱甘肽（GSH 和 GSSG）失衡，并轻微诱导脂质过氧化（增加丙二醛，MDA）。我们的结果表明，氧化应激可能是新烟碱类杀虫剂毒性的一个相关机制，反映在昆虫的发育和生命周期参数上。
