Kalogerak Alexandrai, Tamiolakis Dimitrios, Zoi Iris, Karvela-Kalogeraki Iliana, Karvelas-Kalogerakis Mihailos, Segredakis John, Datseri Galateia
UNIVERSITY OF CRETE, GREECE, MEDICAL FACULTY..
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Acta Biomed. 2018 Jun 7;89(2):265-268. doi: 10.23750/abm.v89i2.5436.
Small cell glioblastoma is a high anaplastic variant of GBM characterized by a monomorphic proliferation of small or medium cells with oval nuclei and scanty cytoplasm.
The cytologic findings of a small cell glioblastoma in 11-year-old male and histologic features of the tumor using immunocytohistochemistry are reported.
The accurate preoperative diagnosis of a small cell glioblastoma is crucial to developing a curative surgical plan. Cytology- confirmed by histology- provides a convenient, safe and effective approach to solving a challenging differential diagnosis.
小细胞胶质母细胞瘤是胶质母细胞瘤的一种高度间变亚型,其特征为小或中等大小细胞呈单形性增殖,细胞核呈椭圆形,细胞质稀少。
报告了一名11岁男性小细胞胶质母细胞瘤的细胞学检查结果以及使用免疫细胞组织化学方法观察到的肿瘤组织学特征。
小细胞胶质母细胞瘤的准确术前诊断对于制定根治性手术方案至关重要。经组织学证实的细胞学检查提供了一种方便、安全且有效的方法来解决具有挑战性的鉴别诊断问题。