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根据纳瓦拉大学动态随访队列中个体的SF-36量表,肥胖和体重增加对生活质量的影响。

The influence of obesity and weight gain on quality of life according to the SF-36 for individuals of the dynamic follow-up cohort of the University of Navarra.

作者信息

Barcones-Molero M F, Sánchez-Villegas A, Martínez-González M A, Bes-Rastrollo M, Martínez-Urbistondo M, Santabárbara J, Martínez J A

机构信息

Instituto de Investigación Sanitaria de Aragón (IIS-IACS Aragón), Hospital Clínico Universitario Lozano Bles», Hospital Universitario Miguel Servet, Centro de Salud Torre Ramona, Zaragoza, España.

Grupo de Investigación en Nutrición, Instituto Universitario de Investigaciones Biomédicas y Sanitarias (IUIBS) , Las Palmas de Gran Canaria, España; Ciber de Fisiopatología de la Obesidad y Nutrición (CIBER OBN), Instituto de Salud Carlos III, Madrid, España.

出版信息

Rev Clin Esp (Barc). 2018 Nov;218(8):408-416. doi: 10.1016/j.rce.2018.05.005. Epub 2018 Jun 27.

Abstract

BACKGROUND

The health-related quality of life is an important element for the comprehensive assessment of overweight and obesity.

OBJECTIVE

To assess the impact of obesity and weight gain on the health-related quality of life of the dynamic cohort of the Follow-up Program of the University of Navarra.

MATERIAL AND METHODS

The analysis included 10,033 participants of the prospective dynamic cohort of the Follow-up Project of the University of Navarra, with a response rate of approximately 90%. The quality of life was measured with the Short Form 36 Health Survey (SF-36) (0, worst quality of life; 100, best quality of life). The statistical analysis was performed with generalized lineal models (mean of each SF-36 domain and 95% CI). A difference of 3 points was considered clinically relevant.

RESULTS

The SF-36 analysis showed that physical function, general health and the physical component summary were inferior in individuals with excess weight and obesity at the start of the study, compared with individuals with normal weight. The study population with unchanged excess weight or obesity after 2 years of follow-up presented lower scores on the SF-36 domains corresponding to physical function, body pain, physical component summary and general health than individuals who maintained the normal weight category according to BMI (kg/m).

CONCLUSIONS

Obesity appears to be associated with a negative impact on health-related quality of life, affecting the physical area more significantly than the psychosocial.

摘要

背景

健康相关生活质量是超重和肥胖综合评估的重要因素。

目的

评估肥胖和体重增加对纳瓦拉大学随访项目动态队列中与健康相关生活质量的影响。

材料与方法

分析纳入了纳瓦拉大学随访项目前瞻性动态队列中的10033名参与者,应答率约为90%。生活质量采用简短健康调查量表(SF-36)进行测量(0分表示最差生活质量;100分表示最佳生活质量)。采用广义线性模型进行统计分析(每个SF-36领域的均值和95%置信区间)。3分的差异被认为具有临床相关性。

结果

SF-36分析显示,与体重正常者相比,研究开始时超重和肥胖个体的身体功能、总体健康状况和身体成分总结得分较低。随访2年后体重超重或肥胖情况未改变的研究人群,在SF-36中与身体功能、身体疼痛、身体成分总结和总体健康状况相关领域的得分低于根据体重指数(kg/m)保持体重正常类别的个体。

结论

肥胖似乎与健康相关生活质量的负面影响有关,对身体方面的影响比对心理社会方面的影响更显著。

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