Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, UK.
Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, UK.
Trends Parasitol. 2018 Aug;34(8):694-711. doi: 10.1016/j.pt.2018.05.004. Epub 2018 Jun 26.
Lymphatic filariasis (LF) and onchocerciasis are two neglected tropical diseases (NTDs) of public health significance targeted for global elimination. The World Health Organization (WHO) African Region is a priority region, with the highest collective burden of LF and onchocerciasis globally. Coendemic loiasis further complicates elimination due to the risk of adverse events associated with ivermectin treatment. A public health framework focusing on health-related data, systematic collection of data, and analysis and interpretation of data is used to highlight the range of innovative surveillance strategies required for filariasis elimination. The most recent and significant developments include: rapid point-of-care test (POCT) diagnostics; clinical assessment tools; new WHO guidelines; open-access online data portals; mHealth platforms; large-scale prevalence maps; and the optimisation of mathematical models.
淋巴丝虫病（LF）和盘尾丝虫病是两种具有公共卫生意义的被忽视热带病（NTD），目标是全球消除。世界卫生组织（WHO）非洲区域是一个优先区域，其 LF 和盘尾丝虫病的集体负担在全球最高。象皮病的共流行进一步使消除工作复杂化，因为伊维菌素治疗相关的不良事件风险。一个以健康相关数据为重点的公共卫生框架，系统地收集数据，并对数据进行分析和解释，用于突出强调消除丝虫病所需的各种创新性监测策略。最近和最重要的发展包括：快速即时检测（POCT）诊断；临床评估工具；新的世卫组织指南；开放获取的在线数据门户；移动健康平台；大规模流行地图；以及数学模型的优化。
