截瘫作为原发性高草酸尿症的一种表现形式。
Paraplegia as a presentation of primary hyperoxaluria.
作者信息
Dieudonné Yannick, Eprinchard Laure, Léon Emilie, Oswald Pierre, Gressel Anne, Carre Sophie, Dimitrov Yves
机构信息
Nephrology Department, CH Haguenau, 67500, Haguenau, France.
Radiology Department, CH Haguenau, Haguenau, France.
出版信息
CEN Case Rep. 2018 Nov;7(2):313-315. doi: 10.1007/s13730-018-0349-7. Epub 2018 Jun 29.
Abstract
30% of the patients suffering from hyperoxaluria type 1 are diagnosed only when they already had reached end-stage renal disease. We report the case of a 57-year-old woman with history of chronic kidney failure presenting with paraplegia due to spinal cord compression by thoracic mass-like lesions. Bone biopsy specimen obtained by decompressive laminectomy revealed calcium oxalate deposits. Once diagnosis of primary hyperoxaluria was confirmed, she underwent haemodialysis with incomplete improvement of her neurological disorders and was registered on the waiting list for transplantation.
摘要
1型高草酸尿症患者中有30%仅在已发展到终末期肾病时才被诊断出来。我们报告了一例57岁女性病例，她有慢性肾衰竭病史，因胸椎肿块样病变压迫脊髓而出现截瘫。减压性椎板切除术后获得的骨活检标本显示有草酸钙沉积。一旦原发性高草酸尿症的诊断得到证实，她接受了血液透析，但神经功能障碍未完全改善，并被列入移植等待名单。
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