Department of Obstetrics and Gynecology, Center for Innate Immunity and Immune Disease and Department of Global Health, University of Washington, Seattle, WA, USA; Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden.
Department of Epidemiology, School of Public Health and Department of Educational Psychology, School Psychology Program, University of Washington, Seattle, WA, USA.
Trends Microbiol. 2018 Sep;26(9):729-732. doi: 10.1016/j.tim.2018.05.011. Epub 2018 Jun 27.
Pregnancy infections with Zika virus are associated with a spectrum of fetal brain injuries beyond microcephaly. Nonmicrocephalic children exposed to Zika virus in utero or early life should undergo neurodevelopmental testing to identify deficits and allow for early intervention. Additionally, long-term monitoring for higher order neurocognitive deficits should be implemented.
寨卡病毒感染与胎儿脑损伤有关,除小头畸形外,还包括一系列脑损伤。在宫内或生命早期暴露于寨卡病毒的非小头畸形儿童应进行神经发育测试,以确定缺陷并进行早期干预。此外,还应实施长期监测,以发现更高阶的神经认知缺陷。