Restrepo Marcos I, Sibila Oriol, Anzueto Antonio
South Texas Veterans Health Care System, San Antonio, TX, USA.
Veterans Evidence Based Research Dissemination and Implementation Center (VERDICT) (MR), San Antonio, TX, USA.
Tuberc Respir Dis (Seoul). 2018 Jul;81(3):187-197. doi: 10.4046/trd.2018.0030.
Chronic obstructive pulmonary disease (COPD) is a frequent comorbid condition associated with increased morbidity and mortality. Pneumonia is the most common infectious disease condition. The purpose of this review is to evaluate the impact of pneumonia in patients with COPD. We will evaluate the epidemiology and factors associated with pneumonia. We are discussing the clinical characteristics of COPD that may favor the development of infections conditions such as pneumonia. Over the last 10 years, there is an increased evidence that COPD patients treated with inhaled corticosteroids are at increased risk to develp pneumonia. We will review the avaialbe information as well as the possible mechanism for this events. We also discuss the impact of influenza and pneumococcal vaccination in the prevention of pneumonia in COPD patients.
慢性阻塞性肺疾病（COPD）是一种常见的合并症，与发病率和死亡率增加相关。肺炎是最常见的感染性疾病。本综述的目的是评估肺炎对COPD患者的影响。我们将评估肺炎的流行病学及相关因素。我们正在讨论可能有利于诸如肺炎等感染性疾病发生的COPD临床特征。在过去10年中，越来越多的证据表明，接受吸入性糖皮质激素治疗的COPD患者发生肺炎的风险增加。我们将回顾关于这一事件的现有信息以及可能的机制。我们还将讨论流感疫苗和肺炎球菌疫苗在预防COPD患者肺炎方面的作用。
