Chiu Chih-Hui, Yang Tsung-Jen, Liang Hong Jen, Chang Cheng-Kang, Wu Ching-Lin
Graduate Program in Department of Exercise Health Science, National Taiwan University of Sport, Taichung 40404, Taiwan, Republic of China.
Department of Physical Education, National Taiwan Normal University, Taipei 10610, Taiwan, Republic of China.
Chin J Physiol. 2018 Jun;61(3):181-187. doi: 10.4077/CJP.2018.BAG570.
High plasma triglyceride (TG) concentration in fasting state could cause hemorheological abnormality, thus increasing the incidence of metabolic diseases. Exercise has been reported to effectively reduce postprandial TG response. This study aimed to investigate whether a single bout of pre-prandial exercise can affect lipemia and hemorheological variables after a high-fat meal. Nine healthy young male subjects completed two experimental trials. The subjects walked for 1 h at 50% maximal oxygen uptake (V̇O₂max) (the exercise, EX trial), or rested (the control, CON trial). In the next morning, the subjects consumed a high-fat meal, and the postprandial lipemia and hemorheological responses were monitored for 6 h. The results showed that postprandial plasma TG concentrations were significantly lower in the EX trial compared to the CON trial. The postprandial low-density lipoproteins (LDL) concentration declined in the first 2 h and then gradually returned to the baseline level in both trials. The postprandial blood viscosity also decreased in the CON trial. There was no significant difference in postprandial blood viscosity, red blood cell (RBC) deformation index and aggregation degree between the trials. There was no significant correlation between plasma TG concentration and blood viscosity. In conclusion, brisk walking effectively reduced postprandial TG concentration, but has no significant impact on postprandial blood viscosity, RBC deformation index and RBC aggregation index.
空腹状态下高血浆甘油三酯（TG）浓度可导致血液流变学异常，从而增加代谢性疾病的发病率。据报道，运动可有效降低餐后TG反应。本研究旨在调查单次餐前运动是否会影响高脂餐后的血脂和血液流变学指标。九名健康年轻男性受试者完成了两项实验。受试者以最大摄氧量（V̇O₂max）的50%步行1小时（运动组，EX试验），或休息（对照组，CON试验）。次日早晨，受试者食用高脂餐，并监测餐后6小时的血脂和血液流变学反应。结果显示，与CON试验相比，EX试验中餐后血浆TG浓度显著降低。在两项试验中，餐后低密度脂蛋白（LDL）浓度在前2小时下降，然后逐渐恢复到基线水平。CON试验中餐后血液粘度也降低。试验之间餐后血液粘度、红细胞（RBC）变形指数和聚集度无显著差异。血浆TG浓度与血液粘度之间无显著相关性。总之，快走可有效降低餐后TG浓度，但对餐后血液粘度、RBC变形指数和RBC聚集指数无显著影响。
