Kolifa M, Petridou A, Mougios V
Department of Physical Education and Sport Science, Aristotle University of Thessaloniki, 541 24, Greece.
Eur J Clin Nutr. 2004 Oct;58(10):1327-35. doi: 10.1038/sj.ejcn.1601968.
Prior exercise has been repeatedly shown to reduce lipemia after meals of exaggerated fat content (over 60% of total energy). The aim of the present study was to investigate whether the same applies to meals closer to the composition of the typical Western diet and explore whether exercise affects the release of dietary fat into the bloodstream.
Randomized counterbalanced.
Laboratory.
Nine healthy young male volunteers.
Subjects consumed a meal of moderate fat content (35% of total energy, 0.66 g/kg body mass) 14 h after having either cycled for 1 h at 70-75% of maximal heart rate or rested. Macadamia nuts were used as the main source of dietary fat to trace its entry into the circulation because of their unusual fatty acid composition. Blood samples were drawn before the meal and for 8 h postprandially.
Plasma triacylglycerol concentrations and total area under the triacylglycerol concentration vs time curve (AUC) were significantly lower after exercise (P = 0.001 and 0.003, respectively; effect size for the latter, 0.84). However, incremental (above baseline) AUC was not affected by exercise significantly. When controlling for differences in baseline plasma concentrations, only the fatty acids that were more abundant in the meal than in plasma triacylglycerols were decreased in the early postprandial period following exercise, implying either a suppressive effect of exercise on the rate of triacylglycerol release from the intestine or a more rapid chylomicron clearance after meal consumption.
Exercise performed between 15 and 14 h before a meal of moderate fat content reduced postprandial lipemia, mainly by lowering fasting triacylglycerols. The effect of exercise on postprandial triacylglycerol metabolism may be mediated, at least in part, by attenuated release of dietary fat from the intestine.
先前的研究已反复表明，进行运动可降低摄入脂肪含量过高（超过总能量的60%）的餐后血脂水平。本研究的目的是调查对于更接近典型西方饮食组成的餐食，运动是否同样具有此效果，并探究运动是否会影响膳食脂肪释放到血液中。
随机平衡设计。
实验室。
9名健康年轻男性志愿者。
受试者在以最大心率的70 - 75%进行1小时骑行或休息14小时后，食用一顿脂肪含量适中（占总能量的35%，0.66克/千克体重）的餐食。由于澳洲坚果独特的脂肪酸组成，将其作为膳食脂肪的主要来源以追踪其进入循环系统的情况。在餐前及餐后8小时采集血样。
运动后血浆三酰甘油浓度及三酰甘油浓度随时间变化曲线下的总面积（AUC）显著降低（分别为P = 0.001和0.003；后者的效应量为0.84）。然而，运动对餐后三酰甘油浓度相对于基线的增量AUC没有显著影响。在控制基线血浆浓度差异后，运动后仅在餐后早期，餐食中比血浆三酰甘油中更丰富的脂肪酸含量降低，这意味着运动对肠道三酰甘油释放速率有抑制作用，或者在进食后乳糜微粒清除更快。
在摄入脂肪含量适中的餐食前15至14小时进行运动可降低餐后血脂水平，主要是通过降低空腹三酰甘油水平实现的。运动对餐后三酰甘油代谢的影响可能至少部分是由肠道膳食脂肪释放减少介导的。
