Hosseini Seyed Reza, Zabihi Ali, Jafarian Amiri Seyedeh Roghayeh, Bijani Ali
Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Nursing Care Research Center, Babol University of Medical Sciences, Babol, Iran.
J Midlife Health. 2018 Apr-Jun;9(2):97-103. doi: 10.4103/jmh.JMH_87_17.
Older people are at risk for polypharmacy due to multiple chronic diseases. Considering the lack of information in this regard, the aim of this study was to investigate the state of polypharmacy among the elderly in the city of Amirkola in northern part of Iran.
This descriptive/analytical cross-sectional study is a part of Amirkola Health and Aging Project that was conducted on 1616 individuals aged 60 years and over. The data about medications were gathered through interviews and observation of prescriptions and medications consumed by patients. The data were analyzed by SPSS software version 18, and ≤ 0.05 was regarded significant.
In this study, 1616 individuals including 883 men (54.6%) and 733 women (45.3%) were investigated. The average age of individuals was 69.37 ± 7.42. Among the investigated individuals, 526 including 368 men (41.7%) and 158 women (21.6%) consumed no medications. The prevalence of polypharmacy in this study was 23.1%, which was 32.7% in women and 15.2% in men (odds ratio = 1.51, 95% confidence interval: 1.10-1.93). The most prevalent group of medications used in both genders was cardiovascular drugs.
Regarding the considerable prevalence of polypharmacy among the elderly, especially in aged women, serious efforts are required to manage polypharmacy. Provision of educational programs for physicians, personnel of pharmacies, and the staff of health-care centers in order for appropriate and safe consumption of medications in aged people is absolutely necessary.
由于多种慢性疾病，老年人面临多重用药的风险。鉴于这方面信息的缺乏，本研究旨在调查伊朗北部阿米拉科拉市老年人多重用药的状况。
这项描述性/分析性横断面研究是阿米拉科拉健康与老龄化项目的一部分，该项目对1616名60岁及以上的个体进行了研究。通过访谈以及观察患者的处方和所服用的药物来收集用药数据。数据使用SPSS 18软件进行分析，P≤0.05被视为具有统计学意义。
本研究共调查了1616名个体，其中男性883人（54.6%），女性733人（45.3%）。个体的平均年龄为69.37±7.42岁。在被调查个体中，526人（包括368名男性，占41.7%；158名女性，占21.6%）未服用任何药物。本研究中多重用药的患病率为23.1%，其中女性为32.7%，男性为15.2%（优势比=1.51，95%置信区间：1.10 - 1.93）。男女使用最普遍的药物类别均为心血管药物。
鉴于老年人中多重用药的患病率相当高，尤其是老年女性，需要做出认真努力来管理多重用药问题。为医生、药剂师和医疗保健中心工作人员提供教育项目，以确保老年人合理、安全用药是绝对必要的。
