Ross D W, Kaplow L S
Arch Pathol Lab Med. 1985 Nov;109(11):1005-6.
The discovery of hereditary deficiency of myeloperoxidase (MPO) in neutrophils and monocytes of affected individuals has been based on the absence of cytochemical staining in these peripheral blood cells. We report that an immunocytochemical method shows more sensitivity than either the benzidine or 4-chloro-1-naphthol cytochemical methods. In MPO-deficient subjects, immunocytochemistry detects a marked decrease, but not absence, of MPO.
在受影响个体的中性粒细胞和单核细胞中发现遗传性髓过氧化物酶（MPO）缺乏，是基于这些外周血细胞中细胞化学染色的缺失。我们报告一种免疫细胞化学方法比联苯胺或4-氯-1-萘酚细胞化学方法更具敏感性。在MPO缺乏的受试者中，免疫细胞化学检测到MPO明显减少，但并非完全缺失。
