Nahmias Jeffry, Doben Andrew, DeBusk George, Winston Sue, Alouidor Reginald, Kaye Thomas, Patterson Lisa, Garb Jane, Gross Ronald
Department of Surgery, University of California, Irvine, Orange, California, USA.
Am Surg. 2018 May 1;84(5):652-657.
In 2010, 2.5 million people sustained a traumatic brain injury (TBI), with an estimated 75 per cent being mild TBI. Mild TBI is defined as a Glasgow Coma Scale (GCS) of 13 to 15. Based on recent data and our institutional experience, we hypothesized that mild TBI patients, including patients on aspirin, could be safely managed by trauma surgeons without neurosurgical consultation. Trauma patients admitted to a single Level I trauma center from June 2014 through July 2015 aged 18 years or older were evaluated. Patients with a GCS ≥14, regardless of intoxication, with an epidural or subdural hematoma ≤4 mm, trace or small subarachnoid hemorrhage, and/or nondisplaced skull fracture were prospectively enrolled. The primary outcomes were needed for neurosurgical consultation and intervention. Secondary outcomes included readmission rate and neurologic morbidity and mortality rate. Of 1341 trauma admits, 77 were enrolled. No patients required neurosurgical intervention. Only 1/75 (1.3%) patients required neurosurgical consultation. Outpatient follow-up was achieved with 75/77 (97.4%) patients. No mortalities, major neurologic morbidities, or readmissions were observed (95% confidence interval 0-4%). None of the 21 patients on aspirin required neurosurgical intervention and only 1/21 (4.8%) patients required neurosurgical consultation with no mortalities observed at follow-up. Management of mild TBI can be safely accomplished by trauma surgeons without routine neurosurgical consultation. Larger multicenter prospective studies are required to evaluate our finding that this also may be safe in patients taking aspirin.
2010年,有250万人遭受创伤性脑损伤(TBI),其中估计75%为轻度TBI。轻度TBI被定义为格拉斯哥昏迷量表(GCS)评分为13至15分。基于近期数据和我们机构的经验,我们推测轻度TBI患者,包括服用阿司匹林的患者,在无需神经外科会诊的情况下可由创伤外科医生安全处理。对2014年6月至2015年7月期间入住单一一级创伤中心、年龄在18岁及以上的创伤患者进行了评估。前瞻性纳入了GCS≥14分、无论是否中毒、硬膜外或硬膜下血肿≤4mm、微量或少量蛛网膜下腔出血和/或无移位颅骨骨折的患者。主要结局是是否需要神经外科会诊和干预。次要结局包括再入院率以及神经功能障碍和死亡率。在1341例创伤患者中,77例被纳入。没有患者需要神经外科干预。只有77例中的1例(1.3%)患者需要神经外科会诊。77例患者中有75例(97.4%)实现了门诊随访。未观察到死亡、严重神经功能障碍或再入院情况(95%置信区间0 - 4%)。21例服用阿司匹林的患者中,无一例需要神经外科干预,只有21例中的1例(4.8%)患者需要神经外科会诊,随访期间未观察到死亡情况。轻度TBI的处理可由创伤外科医生安全完成,无需常规神经外科会诊。需要开展更大规模的多中心前瞻性研究来评估我们的这一发现,即在服用阿司匹林的患者中这样做也可能是安全的。