Department of Institute of Clinical Physiology, National research Council, Via Moruzzi 1, Pisa 56214, Italy.
Heart Fail Clin. 2018 Jul;14(3):333-337. doi: 10.1016/j.hfc.2018.02.008.
Most healthy subjects can develop a subclinical interstitial pulmonary edema that is a complex and multifactor phenomenon, still with unanswered questions, and might be one line of defense against the development of severe symptomatic lung edema. Whether the acute, reversible increase in lung fluid content is really an innocent and benign part of the adaptation to extreme physiologic condition or rather the clinically relevant marker of an individual vulnerability to life-threatening high altitude pulmonary edema remains to be established in future studies. Thus the question if encouraging more conservative habits to climb is right or not remains open.
大多数健康受试者可发展为亚临床间质性肺水肿，这是一种复杂的、多因素的现象，仍有许多问题尚未得到解答，可能是机体对抗严重症状性肺水肿发生的一道防线。急性、可逆性肺内液体含量增加是否确实是机体对极端生理条件适应的一个无辜且良性的部分，或者是对致命性高原肺水肿个体易感性的临床相关标志物，这仍有待于未来的研究来确定。因此，鼓励更保守的登山习惯是否正确的问题仍悬而未决。
