Department of Psychology, Charles Schmidt College of Science, Florida Atlantic University, Davie, Florida.
Alcohol Clin Exp Res. 2018 Sep;42(9):1815-1822. doi: 10.1111/acer.13830. Epub 2018 Jul 25.
Links between response inhibition and young adult problematic drinking (e.g., binge drinking) have been established, but only to an extent. Considering the presence of some inconsistent findings associated with these 2 variables, this study proposes the need to investigate the extent in which different inhibitory subcomponents are associated with binge drinking behaviors of the same sample.
Through the use of a 6-month longitudinal design, changes in Alcohol Use Questionnaire (AUQ) binge score of 163 college students (50.3% female) with a mean age of 21.06 years (SD = 1.83) were correlated with performance on 3 different inhibitory control tasks. Each task was selected to assess separate inhibitory subcomponents: Stop Signal Task (e.g., cancellation of a response), Go/No-Go Task (e.g., withholding of a response), and Simon Task (e.g., inhibiting response interference). Response inhibition was also compared between 2 groups, those who had a substantial increase in AUQ binge score during participation (inAUQ) and those who had a substantial decrease in AUQ binge score (deAUQ).
A significant correlation was found with a change in AUQ binge score and stop signal reaction time among females only, where an increase in binge drinking score positively correlated with a reduced ability to cancel an already-initiated inhibitory response. Differences in inhibitory performance, where inAUQ performed worse than deAUQ, approached significance.
The results suggest that the cancellation of a prepotent response, as opposed to the withholding of response or interference inhibition, is a more sensitive inhibitory measure associated with increases in binge drinking behavior among female young adult college students. Further exploration of inhibitory subcomponents relative to substance use is greatly needed (e.g., more extensive longitudinal designs and neuroimaging techniques).
反应抑制与青年期问题性饮酒（如狂饮）之间存在关联，但这种关联的程度有限。鉴于这两个变量存在一些不一致的发现，本研究提出需要调查不同抑制子成分与同一样本的狂饮行为之间的关联程度。
通过使用 6 个月的纵向设计，对 163 名年龄在 21.06 岁（标准差=1.83）的大学生（女性占 50.3%）的酒精使用问卷（AUQ）狂饮得分的变化与 3 种不同的抑制控制任务的表现相关联。每项任务都被选择来评估单独的抑制子成分：停止信号任务（例如，取消反应）、Go/No-Go 任务（例如，抑制反应）和 Simon 任务（例如，抑制反应干扰）。还比较了 2 组之间的反应抑制，一组是在参与期间 AUQ 狂饮得分有显著增加（inAUQ）的组，另一组是 AUQ 狂饮得分有显著减少（deAUQ）的组。
仅在女性中发现 AUQ 狂饮得分的变化与停止信号反应时间之间存在显著相关性，狂饮得分的增加与已经启动的抑制反应的取消能力降低呈正相关。抑制表现的差异，inAUQ 组的表现比 deAUQ 组差，接近显著水平。
结果表明，与抑制反应的启动相比，取消一个强烈的反应（而不是抑制反应或抑制干扰）是一种更敏感的抑制测量方法，与女性青年大学生狂饮行为的增加有关。需要进一步探索抑制子成分与物质使用的关系（例如，更广泛的纵向设计和神经影像学技术）。
