Lee Sook-Hyun, Kim Gyurin, Kim Chul-Eung, Ryu Seunghyong
Department of Mental Health Research, National Center for Mental Health, Seoul, Republic of Korea.
Mental Health Research Institute, National Center for Mental Health, Seoul, Republic of Korea.
Psychiatry Investig. 2018 Aug;15(8):811-817. doi: 10.30773/pi.2018.04.15.1. Epub 2018 Jul 4.
This study aimed to investigate clinical factors contributing to the low physical activity (PA) of patients with chronic schizophrenia.
PA was measured in 50 outpatients with chronic schizophrenia using the International Physical Activity Questionnaire Short Form (IPAQ-SF). Psychopathology, psychosocial functioning, and extrapyramidal symptoms were assessed using the 18 item-Brief Psychiatric Rating Scale (BPRS-18), Global Assessment of Functioning (GAF), and Drug-Induced Extrapyramidal Symptom Scale (DIEPSS), respectively. We examined differences in these clinical variables between "inactive," "minimally active," and "health enhancing physical activity" groups. Linear regression analysis was used to examine the clinical factors explaining low PA levels in patients with schizophrenia.
Subjects spent an average of 130.18±238.89 min/wk on moderate/vigorous-intensity PA and only 26% of them met the recommended PA guideline of 150 minutes of at least moderate PA per week. The inactive group showed significantly higher BPRS-18 and DIEPSS scores, and a lower GAF score than the other groups. Linear regression analysis showed that DIEPSS scores independently explained the amount of total PA (p=0.001) and time spent being sedentary (p=0.028).
This study provides preliminary evidence that extrapyramidal symptoms could be a major impediment to the PA of patients with schizophrenia.
本研究旨在调查导致慢性精神分裂症患者身体活动水平低的临床因素。
使用国际身体活动问卷简表(IPAQ-SF)对50名慢性精神分裂症门诊患者的身体活动进行测量。分别使用18项简明精神病评定量表(BPRS-18)、功能总体评定量表(GAF)和药物所致锥体外系症状量表(DIEPSS)评估精神病理学、心理社会功能和锥体外系症状。我们检查了“不活动”、“轻度活动”和“促进健康的身体活动”组之间这些临床变量的差异。采用线性回归分析来检查解释精神分裂症患者低身体活动水平的临床因素。
受试者每周进行中等/高强度身体活动的平均时间为130.18±238.89分钟,只有26%的人达到了每周至少150分钟中等强度身体活动的推荐身体活动指南。与其他组相比,不活动组的BPRS-18和DIEPSS得分显著更高,GAF得分更低。线性回归分析表明,DIEPSS得分独立解释了总身体活动量(p=0.001)和久坐时间(p=0.028)。
本研究提供了初步证据,表明锥体外系症状可能是精神分裂症患者身体活动的主要障碍。