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中国北京一所寄宿制高中由GII.P16-GII.2诺如病毒引起的食源性急性胃肠炎暴发:一项病例对照研究

A foodborne acute gastroenteritis outbreak caused by GII.P16-GII.2 norovirus in a boarding high school, Beijing, China: a case-control study.

作者信息

Guo Xin-Hui, Kan Zhen, Liu Bai-Wei, Li Li-Li

机构信息

Fangshan Center for Disease Control and Prevention, Fangshan, Beijing, China.

Beijing Center for Disease Control and Prevention, Beijing, China.

出版信息

BMC Res Notes. 2018 Jul 3;11(1):439. doi: 10.1186/s13104-018-3532-1.

Abstract

OBJECTIVE

In December 2017, an acute gastroenteritis outbreak involving 61 students occurred in a boarding high school in Beijing, China. We conducted an outbreak investigation immediately in order to determine the cause of this outbreak and provide effective control measures.

RESULTS

The laboratory inspection showed that this outbreak was caused by GII.P16-GII.2 norovirus. Risk factor analysis indicated that the lunch provided by Cafeteria 1 on Dec 12 might be the risk factor of the outbreak with an odds ratio (OR) of 3.800 (95% confidence interval [CI] 1.089-13.258). Additionally, a tray line server of Cafeteria 1 was found to have gastro-enteral symptoms recently. Based on the clinical symptoms and epidemiology investigation, the symptomatic server was considered to be the possible source of infection.

摘要

目的

2017年12月,中国北京一所寄宿制高中发生了一起涉及61名学生的急性肠胃炎暴发事件。我们立即开展了疫情调查,以确定此次暴发的原因并提供有效的控制措施。

结果

实验室检测表明,此次暴发是由GII.P16-GII.2诺如病毒引起的。危险因素分析表明,12月12日食堂1提供的午餐可能是此次暴发的危险因素,比值比(OR)为3.800(95%置信区间[CI]1.089-13.258)。此外,发现食堂1的一名托盘流水线服务员近期出现肠胃症状。根据临床症状和流行病学调查,该有症状的服务员被认为是可能的感染源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4041/6029270/d6b66a6dbce1/13104_2018_3532_Fig1_HTML.jpg

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