Kohl Louis P, Isselbacher Eric M, Majahalme Nilla, Evangelista Arturo, Russo Mark J, Hutchison Stuart, Bossone Eduardo, Suzuki Toru, Pyeritz Reed E, Gleason Thomas G, Conklin Lori D, Montgomery Daniel G, Nienaber Christoph A, Eagle Kim A, Harris Kevin M
Minneapolis Heart Institute Foundation at Abbott-Northwestern Hospital, Minneapolis, Minnesota; Hennepin County Medical Center, Minneapolis, Minnesota.
Thoracic Aortic Center, Massachusetts General Hospital, Boston, Massachusetts.
Am J Cardiol. 2018 Aug 15;122(4):689-695. doi: 10.1016/j.amjcard.2018.04.042. Epub 2018 Jun 30.
The DeBakey classification divides type A acute aortic dissection (AAD) into type I and type II; the latter limited to the ascending aorta. We endeavored to examine differences in DeBakey groups in a contemporary registry. We divided 1,872 patients with noniatrogenic AAD from the International Registry of Acute Aortic Dissection into type I (n = 1691, 90.3%) and type II (n = 181, 9.7%). Patients with type II AAD were older. On presentation, patients with type I AAD reported more back and abdominal pain and were more likely to have pulse deficit. Intramural hematoma was more frequent in type II AAD. Most patients with both types were treated surgically. Lower rates of renal failure, coma, mesenteric and limb ischemia were noted in those with type II AAD. In-hospital death was less frequent (16.6% vs 22.5%) after type II AAD, a trend that did not reach significance. There was no difference in the incidence of new dissection, rapid aortic growth, late aortic intervention or survival at 5 years. In conclusion, AAD limited to the ascending aorta (DeBakey type II) appears to be associated with improved clinical outcomes compared with dissection that extend to the aortic arch or beyond. Although fewer dissection-related complications were noted in patients presenting with type II AAD, as was a trend toward reduced in-hospital mortality, 5-year survival and descending aortic sequelae are not reduced in this contemporary report from International Registry of Acute Aortic Dissection.
德巴基分类法将 A 型急性主动脉夹层(AAD)分为 I 型和 II 型;后者仅限于升主动脉。我们试图在一个当代注册研究中研究德巴基分组之间的差异。我们将国际急性主动脉夹层注册研究中的 1872 例非医源性 AAD 患者分为 I 型(n = 1691,90.3%)和 II 型(n = 181,9.7%)。II 型 AAD 患者年龄更大。就诊时,I 型 AAD 患者报告的背部和腹痛更多,且更有可能出现脉搏缺损。壁内血肿在 II 型 AAD 中更常见。大多数两型患者均接受了手术治疗。II 型 AAD 患者的肾衰竭、昏迷、肠系膜和肢体缺血发生率较低。II 型 AAD 后的住院死亡率较低(16.6% 对 22.5%),这一趋势未达到显著水平。新夹层的发生率、主动脉快速生长、晚期主动脉干预或 5 年生存率无差异。总之,与延伸至主动脉弓或更远部位的夹层相比,仅限于升主动脉的 AAD(德巴基 II 型)似乎与更好的临床结局相关。尽管 II 型 AAD 患者的夹层相关并发症较少,且住院死亡率有降低趋势,但在国际急性主动脉夹层注册研究的这份当代报告中,5 年生存率和降主动脉后遗症并未降低。