Zhang Ying, Huang Xiaochun, Peng Chuangliang, Wang Yongbin, Wu Qian, Wu Zhen, Shao Hongyan, Wang Wei
Department of Respiratory Medicine, The Second Hospital of Shandong University, Jinan, China.
Department of Thoracic, The Second Hospital of Shandong University, Jinan, China.
J Cancer Res Ther. 2018 Jun;14(Supplement):S533-S535. doi: 10.4103/0973-1482.176419.
Primary pulmonary epithelioid angiosarcoma is an extremely rare malignancy. Herein, we report the case of an elderly Chinese patient with primary pulmonary epithelioid angiosarcoma. The 72-year-old man presented with a 1-month history of persistent hemoptysis and left chest pain and weight loss of 3 kg. A chest computed tomography (CT) scan revealed two masses (maximum size 3.0 cm × 2.0 cm and 0.8 cm × 0.5 cm) in right lower lobe. We performed a left thoracotomy for tumor resection. Pathological examination showed that there was a significant amount of hemorrhage, fibrinous exudates, degeneration, and necrosis. With immunohistochemical analysis, tumor cells had strong expression of CD34, FLI-1, vimentin. Morphological and immunohistochemical findings supported the diagnosis of epithelioid angiosarcoma.
原发性肺上皮样血管肉瘤是一种极其罕见的恶性肿瘤。在此，我们报告一例老年中国原发性肺上皮样血管肉瘤患者。该72岁男性有1个月持续咯血、左胸痛病史，体重减轻3kg。胸部计算机断层扫描（CT）显示右下叶有两个肿块（最大尺寸为3.0cm×2.0cm和0.8cm×0.5cm）。我们进行了左开胸手术以切除肿瘤。病理检查显示有大量出血、纤维蛋白渗出、变性和坏死。免疫组化分析显示，肿瘤细胞CD34、FLI-1、波形蛋白呈强表达。形态学和免疫组化结果支持上皮样血管肉瘤的诊断。
