重水诱导海胆幼虫发生外胚层化。

Exogastrulation induced by heavy water in sea urchin larvae.

作者信息

Hoshi M

出版信息

Cell Differ. 1979 Dec;8(6):431-5. doi: 10.1016/0045-6039(79)90039-3.

Abstract

Replacement of H2O with D2O in seawater causes exogastrulation in larvae of the sea urchins, Hemicentrotus pulcherrimus, Strongylocentrotus intermedius and S. nudus. When larvae at any stages before mesenchymal blastula stage are transferred to 40% D2O-seawater all of them develop gradually to exogastrulae and finally up to plutei with evaginated archenterons. Effects of D2O are partly reversible at limited steps of the way to exogastrulation. Fertilisation and cleavage are not affected appreciably by D2O (50% or less) except for the delay of cleavage.

摘要

用重水（D₂O）取代海水中的水会导致海胆幼虫（光棘球海胆、中间球海胆和裸海胆）出现外胚层外翻。当间充质囊胚期之前任何阶段的幼虫转移到含40% D₂O的海水中时，它们都会逐渐发育成外胚层外翻的幼虫，最终发育成原肠外翻的长腕幼虫。在向外胚层外翻发育的有限步骤中，D₂O的影响部分是可逆的。除了卵裂延迟外，受精和卵裂不受D₂O（50%或更低）的明显影响。