A unique aminoglycoside-O-phosphorylating activity mediating resistance to aminoglycosides in Escherichia coli.
作者信息
Santanam P, Maino L, Kayser F H
出版信息
J Antimicrob Chemother. 1985 Sep;16(3):401-2. doi: 10.1093/jac/16.3.401.
PMID:2997102
Abstract
摘要
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A unique aminoglycoside-O-phosphorylating activity mediating resistance to aminoglycosides in Escherichia coli.一种独特的氨基糖苷 - O - 磷酸化活性介导大肠杆菌对氨基糖苷类药物的耐药性。
J Antimicrob Chemother. 1985 Sep;16(3):401-2. doi: 10.1093/jac/16.3.401.
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Aminoglycoside-phosphotransferases APH(3')-IV and APH(3") synthesized by a strain of Campylobacter coli.由一株大肠弯曲菌合成的氨基糖苷磷酸转移酶APH(3')-IV和APH(3")
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The identification of the aminoglycoside-phosphorylating enzymes APH(2'') and APH(3') from the characterization of their reaction products by high performance liquid chromatography.通过高效液相色谱法对其反应产物进行表征，从而鉴定氨基糖苷磷酸化酶APH(2'')和APH(3')。
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Failure of the disk diffusion test to detect tobramycin resistance in kanamycin-resistant Escherichia coli strains.纸片扩散法未能检测出耐卡那霉素大肠杆菌菌株对妥布霉素的耐药性。
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Biochemical mechanism of resistance to aminoglycosidic antibiotics.对氨基糖苷类抗生素耐药的生化机制。
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Overproduction of 3'-aminoglycoside phosphotransferase type I confers resistance to tobramycin in Escherichia coli.I型3'-氨基糖苷磷酸转移酶的过量产生赋予大肠杆菌对妥布霉素的抗性。
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Amikacin resistance associated with a plasmid-borne aminoglycoside phosphotransferase in Escherichia coli.大肠杆菌中与质粒携带的氨基糖苷磷酸转移酶相关的阿米卡星耐药性
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[Aminoglycoside-3'-phosphotransferase I from aminoglycoside-polyresistant strain E. coli 182].[来自氨基糖苷多抗性菌株大肠杆菌182的氨基糖苷-3'-磷酸转移酶I]
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High-level amikacin resistance in Escherichia coli due to phosphorylation and impaired aminoglycoside uptake.大肠杆菌中由于磷酸化和氨基糖苷摄取受损导致的高水平阿米卡星耐药性。
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Susceptibility to tobramycin determined by a modified agar dilution method with a high inoculum.采用高接种量改良琼脂稀释法测定对妥布霉素的敏感性。
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