由一株大肠弯曲菌合成的氨基糖苷磷酸转移酶APH(3')-IV和APH(3")

Aminoglycoside-phosphotransferases APH(3')-IV and APH(3") synthesized by a strain of Campylobacter coli.

作者信息

Rivera M J, Castillo J, Martin C, Navarro M, Gomez-Lus R

出版信息

J Antimicrob Chemother. 1986 Aug;18(2):153-8. doi: 10.1093/jac/18.2.153.

DOI:10.1093/jac/18.2.153

PMID:3019983

Abstract

Campylobacter coli strain 981 of animal origin was resistant to erythromycin, tetracycline, streptomycin, kanamycin, ribostamycin, neomycin, paromomycin, lividomycin, and butirosin. Resistance to aminoglycosides of strain 981 was mediated by phosphotransferases APH (3') type-IV and APH (3"). C. coli 981 harboured three plasmids of 24, 34, and 40 Megadaltons respectively. None of these plasmids were transferable to Escherichia coli K-12 by conjugation.

摘要

动物源的空肠弯曲菌菌株981对红霉素、四环素、链霉素、卡那霉素、核糖霉素、新霉素、巴龙霉素、青紫霉素和丁胺卡那霉素耐药。菌株981对氨基糖苷类的耐药性由IV型磷酸转移酶APH(3')和APH(3")介导。空肠弯曲菌981分别携带三个大小为24、34和40兆道尔顿的质粒。这些质粒均不能通过接合转移至大肠杆菌K-12。