School of Life Science, Jilin Agricultural University, Jilin, China.
Department of Animal Nutrition, Sylhet Agricultural University, Sylhet, Bangladesh.
J Sci Food Agric. 2019 Jan 30;99(2):703-710. doi: 10.1002/jsfa.9236. Epub 2018 Aug 13.
Medicinal mushrooms contain biologically active substances that can be used as an immune-modulating agent in poultry. The present study aimed to investigate the effects of Flammulina velutipes mushroom waste (FVW) on performance, immune response and serum immunity in growing layer hens.
No significant differences (P > 0.05) were observed with respect to average daily feed intake, body weight gain and feed conversion ratio among the experimental groups during the entire study period (1-70 days). Antibody titers against Newcastle disease and infectious bronchitis were higher (P < 0.05) in the FVW fed groups than in the control and antibiotic groups. On day 28, serum immunoglobulin (Ig)A and IgG were higher (P < 0.05) in the 6% FVW group than in the control and antibiotic fed groups. On day 70, serum IgA was higher (P < 0.05) in FVW fed groups than in the control group; IgG was higher (P < 0.05) in the FVW groups than in the control and antibiotic groups. However, IgM was higher (P < 0.05) in both the 4% and 6% FVW groups than in the control and antibiotic groups for both experimental periods. Serum cytokine interleukin (IL)-2 and tumor necrosis factor-α concentrations were significantly higher (P < 0.05) in both the 4% and 6% FVW grousp than in the control and antibiotic groups; IL-4 was significantly higher (P < 0.05) in the FVW groups than in the control group; and IL-6 was significantly higher (P < 0.05) in the 6% FVW group than in the control and antibiotic groups.
FVW at the 6% level can be used as a potential phytogenic feed stuff in growing layer hen rations with respect to improving the immune response without affecting normal weight gain. © 2018 Society of Chemical Industry.
药用蘑菇含有生物活性物质，可用作家禽的免疫调节剂。本研究旨在研究金针菇菇渣（FVW）对生长蛋鸡的生产性能、免疫反应和血清免疫的影响。
在整个研究期间（1-70 天），实验组的平均日采食量、体重增加和饲料转化率均无显著差异（P＞0.05）。FVW 组的新城疫和传染性支气管炎抗体滴度均高于对照组和抗生素组（P＜0.05）。第 28 天，6%FVW 组血清免疫球蛋白（Ig）A 和 IgG 高于对照组和抗生素组（P＜0.05）。第 70 天，FVW 组血清 IgA 高于对照组（P＜0.05）；FVW 组 IgG 高于对照组和抗生素组（P＜0.05）。然而，两个 FVW 组的 IgM 均高于对照组和抗生素组（P＜0.05）。两个 FVW 组的血清细胞因子白细胞介素（IL）-2 和肿瘤坏死因子-α浓度均显著高于对照组和抗生素组（P＜0.05）；FVW 组的 IL-4 显著高于对照组（P＜0.05）；6%FVW 组的 IL-6 显著高于对照组和抗生素组（P＜0.05）。
6%水平的 FVW 可作为生长蛋鸡日粮中的一种潜在植物源饲料，在不影响正常体重增加的情况下提高免疫反应。© 2018 化学工业协会。
