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肿瘤生育学——新兴学科而非特殊考量。

Oncofertility-An emerging discipline rather than a special consideration.

机构信息

Kids Cancer Centre, Sydney Children's Hospital, Sydney, Australia.

Nelune Comprehensive Cancer Centre, Prince of Wales Hospital, Sydney, Australia.

出版信息

Pediatr Blood Cancer. 2018 Nov;65(11):e27297. doi: 10.1002/pbc.27297. Epub 2018 Jul 3.

DOI:10.1002/pbc.27297
PMID:29972282
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6150802/
Abstract

Originally absent from the oncologist's consult, then placed in a 'quality of life' rubric, oncofertility should now be an essential part of a comprehensive cancer treatment plan in patients of reproductive age, including adolescents and young adults (AYAs). Oncofertility encompasses the endocrine health of the patient, as well as fertility management options. Thus, pubertal transitions in males and females, bone health, and menstrual health are all part of this discipline, enabling practitioners to work in interdisciplinary teams to solve problems in reproductive health. This review provides a summary of the essential considerations required for the assessement of reproductive risk and choice of fertility preservation options as well as considerations for developing oncofertility services for AYAs.

摘要

起初并未纳入肿瘤医生的咨询范围,而是归入“生活质量”类目,生育力保存现在应成为育龄期(包括青少年和年轻成人)癌症患者综合治疗方案的重要组成部分。生育力保存涵盖患者的内分泌健康和生育力管理选择。因此,男性和女性的青春期过渡、骨骼健康和月经健康都是该学科的一部分,使从业者能够在跨学科团队中合作解决生殖健康问题。这篇综述总结了评估生殖风险和选择生育力保存方案所需的基本注意事项,以及为青少年和年轻成人制定生育力保存服务的注意事项。

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Survey of Fertility Preservation Options Available to Patients With Cancer Around the Globe.全球癌症患者可选择的生育力保存方法调查。
JCO Glob Oncol. 2020 Mar 2;6. doi: 10.1200/JGO.2016.008144. eCollection 2020.
2
Survey of Third-Party Parenting Options Associated With Fertility Preservation Available to Patients With Cancer Around the Globe.全球癌症患者可采用的与生育力保存相关的第三方育儿选择调查。
JCO Glob Oncol. 2020 Mar 2;6. doi: 10.1200/JGO.2017.009944. eCollection 2020.
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Building Oncofertility Core Competency in Developing Countries: Experience From Egypt, Tunisia, Brazil, Peru, and Panama.
Online discussions about cancer and fertility: an analysis of Reddit threads.关于癌症与生育能力的在线讨论:对Reddit主题帖的分析
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Oncofertility Barriers in Nurses Caring for Women with Breast Cancer.照顾乳腺癌女性患者的护士所面临的生育力保护障碍。
Sci Rep. 2025 Mar 1;15(1):7306. doi: 10.1038/s41598-025-91404-2.
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Radiotherapy and Testicular Function: A Comprehensive Review of the Radiation-Induced Effects with an Emphasis on Spermatogenesis.放射治疗与睾丸功能:对辐射诱导效应的全面综述,重点关注精子发生
Biomedicines. 2024 Jul 5;12(7):1492. doi: 10.3390/biomedicines12071492.
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Future Fertility Among Pediatric Cancer Patients: Experiences and Perspectives of Health Workers in a Low-Resource Setting.儿科癌症患者的未来生育能力:资源匮乏环境下卫生工作者的经验和观点。
J Adolesc Young Adult Oncol. 2024 Aug;13(4):637-645. doi: 10.1089/jayao.2024.0011. Epub 2024 Apr 13.
7
Ethical, legal, social, and policy issues of ovarian tissue cryopreservation in prepubertal girls: a critical interpretive review.青春期前女孩卵巢组织冷冻保存的伦理、法律、社会和政策问题:批判性解释性综述。
J Assist Reprod Genet. 2024 Apr;41(4):999-1026. doi: 10.1007/s10815-024-03059-z. Epub 2024 Mar 2.
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Oncofertility: Treatment options from bench to bedside.肿瘤生育学:从实验室到临床的治疗选择。
Cancer Pathog Ther. 2023 May 13;1(4):284-289. doi: 10.1016/j.cpt.2023.05.001. eCollection 2023 Oct.
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Pre-treatment fertility preservation and post-treatment reproduction in long-term survivors of adolescent and young adult (AYA) cancer.青少年和青年成人(AYA)癌症长期幸存者的治疗前生育力保存及治疗后生殖
J Cancer Surviv. 2024 Feb 6. doi: 10.1007/s11764-024-01538-x.
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"Queer Insights": Considerations and Challenges for Assessing Sex, Gender Identity, and Sexual Orientation in Oncofertility Research.《酷儿洞察》:肿瘤生育力研究中评估性别、性别认同和性取向的考量与挑战
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Factors influencing the documentation of fertility-related discussions for adolescents and young adults with cancer.影响癌症青少年及青年生育相关讨论记录的因素。
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Pediatr Blood Cancer. 2018 Aug;65(8):e27087. doi: 10.1002/pbc.27087. Epub 2018 Apr 26.
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Reprod Health. 2018 Jan 5;15(1):2. doi: 10.1186/s12978-017-0441-z.