Gupta Divya, Singh Shubham, Shukla Sangeeta, Shrivastava Sadhana
Reproductive Biology and Toxicology Lab, SOS in Zoology, Jiwaji University, Gwalior, Madhya Pradesh 474011, India.
Department of Zoology, Guru Ghasidas Vishwavidyalaya, Bilaspur (C.G.) 495009, India.
Cancer Pathog Ther. 2023 May 13;1(4):284-289. doi: 10.1016/j.cpt.2023.05.001. eCollection 2023 Oct.
In recent years, there has been continuous improvement in the treatment and diagnosis of cancer, which has led to a significant improvement in the survival rate of cancer patients. Treatments that include chemotherapy, radiotherapy, surgery, or combined therapy have several side effects that may lead to premature ovarian insufficiency in females or substantial male germ cell loss. Reproductive biologists recommend that all patients who are diagnosed with a malignant tumor must undergo a consultation for fertility protection and preservation. In this review, we discuss the background knowledge, methods, and options for fertility preservation and how these new strategies help oncologists, surgeons, pediatricians, and hematologists, conserve fertility and be aware of the concepts, methods, and importance of fertility guards. This review may aid in the advancement of novel personalized methods for fertility preservation according to patients' conditions.
近年来，癌症的治疗和诊断不断改进，这使得癌症患者的生存率有了显著提高。包括化疗、放疗、手术或联合治疗在内的治疗方法有多种副作用，可能导致女性过早出现卵巢功能不全或男性大量生殖细胞损失。生殖生物学家建议，所有被诊断患有恶性肿瘤的患者都必须接受生育保护和保存的咨询。在这篇综述中，我们讨论了生育保存的背景知识、方法和选择，以及这些新策略如何帮助肿瘤学家、外科医生、儿科医生和血液学家保护生育能力，并了解生育保护的概念、方法和重要性。这篇综述可能有助于根据患者情况推进新型个性化生育保存方法的发展。
