皮下组织中脾植入物对无脾动物存活的影响。
INFLUENCE OF SPLENIC IMPLANTS IN THE SUBCUTANEOUS TISSUE ON ASPLENIC ANIMALS SURVIVAL.
作者信息
Teixeira Renan Kleber Costa, Santiago Laryssa de Aquino, Sasaki Yan de Assis, Yamaki Vitor Nagai, Feijó Daniel Haber, Brito Marcus Vinicius Henriques, Yasojima Edson Yuzur, Petroianu Andy
机构信息
Laboratório de Cirurgia Experimental da Faculdade de Medicina da Universidade Estadual do Pará - UEPA, Belém, PA.
Universidade Federal de Minas Gerais - UFMG, Minas Gerais, MG, Brazil.
出版信息
Arq Bras Cir Dig. 2018;31(2):e1364. doi: 10.1590/0102-672020180001e1364. Epub 2018 Jul 2.
BACKGROUND
The best site for splenic implant was not defined, mainly evaluating the functionality of the implant.
AIM
To evaluate the effects of autogenous splenic implantation on the subcutaneous tissue in the survival of splenectomized rats.
METHOD
Twenty-one randomly assigned rats were studied in three groups (n=7): group 1 - manipulation of the abdominal cavity and preservation of the spleen; group 2 - total splenectomy; group 3 - splenectomy and implant of the tissue removed in the subcutaneous. The animals were followed for 90 days postoperatively.
RESULTS
There was a higher mortality in groups 2 (p=0.0072) and 3 (p=0.0172) in relation to group 1. There was no difference between groups 2 and 3 (p=0.9817).
CONCLUSION
The splenic implant in the subcutaneous is ineffective in the survival of rats submitted to splenectomy.
背景
脾植入的最佳部位尚未明确，主要是评估植入物的功能。
目的
评估自体脾植入对脾切除大鼠皮下组织存活情况的影响。
方法
将21只随机分组的大鼠分为三组（每组n = 7）：第1组 - 腹腔操作并保留脾脏；第2组 - 全脾切除术；第3组 - 脾切除术并将切除的组织植入皮下。术后对动物进行90天的随访。
结果
与第1组相比，第2组（p = 0.0072）和第3组（p = 0.0172）的死亡率更高。第2组和第3组之间无差异（p = 0.9817）。
结论
皮下脾植入对接受脾切除术的大鼠存活无效。
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