1型人类嗜T细胞病毒感染患者的抑郁和焦虑障碍：一项设有对照组的横断面研究
Depression and anxiety disorders among patients with human T-cell lymphotropic virus type-1: a cross-sectional study with a comparison group.
作者信息
Rocha-Filho Pedro Augusto Sampaio, Goncalves Liliana Raulino
机构信息
Hospital Universitario Oswaldo Cruz, Universidade de Pernambuco, Recife, PE, Brasil.
Departamento de Neuropsiquiatria, Universidade Federal de Pernambuco, Recife, PE, Brasil.
出版信息
Rev Soc Bras Med Trop. 2018 May-Jun;51(3):357-360. doi: 10.1590/0037-8682-0365-2016.
INTRODUCTION
Studies have linked human T-cell lymphotropic virus type-1 (HTLV-1) to psychiatric disease.
METHODS
Patients with HTLV-1 were compared to patients seen by family doctors using a semi-structured questionnaire and the Hospital Anxiety and Depression Scale.
RESULTS
Participants with (n=58) and without (n=340) HTLV were compared. Anxiety and depression were associated with greater age, being a woman, spastic paraparesis (depression: PR=4.50, 95% CI: 3.10-6.53; anxiety: PR=2.96, 95% CI: 2.08-4.21), and asymptomatic HTLV (depression: PR=4.34, 95% CI: 3.02-6.24; anxiety: PR=2.81, 95% CI: 2.06-3.85).
CONCLUSIONS
Symptomatic and asymptomatic patients with HTLV-1 experienced more anxiety and depression than uninfected patients.
引言
研究已将1型人类嗜T淋巴细胞病毒（HTLV-1）与精神疾病联系起来。
方法
使用半结构化问卷和医院焦虑抑郁量表，将HTLV-1患者与家庭医生诊治的患者进行比较。
结果
对58名携带HTLV-1的参与者和340名未携带HTLV-1的参与者进行了比较。焦虑和抑郁与年龄较大、女性、痉挛性截瘫（抑郁：风险比=4.50，95%置信区间：3.10-6.53；焦虑：风险比=2.96，95%置信区间：2.08-4.21）以及无症状HTLV感染（抑郁：风险比=4.34，95%置信区间：3.02-6.24；焦虑：风险比=2.81，95%置信区间：2.06-3.85）有关。
结论
有症状和无症状的HTLV-1患者比未感染患者经历更多的焦虑和抑郁。
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