Cancer Research UK Cambridge Institute, Li Ka Shing Centre and Department of Oncology, University of Cambridge, Cambridge CB2 0RE, UK.
Cell Metab. 2018 Jul 3;28(1):5-6. doi: 10.1016/j.cmet.2018.06.016.
Tumors interact reciprocally with their hosts' physiology and metabolism, making cancer a systemic disease. In this issue of Cell Metabolism, Borniger et al. (2018) demonstrate this phenomenon by linking the endocrine control of food intake with sleep behavior and liver metabolism in a mouse model of non-metastatic breast carcinoma.
肿瘤与其宿主的生理和代谢相互作用，使癌症成为一种全身性疾病。在本期《细胞代谢》中，Borniger 等人（2018）通过链接非转移性乳腺癌小鼠模型中的内分泌控制食物摄入与睡眠行为和肝脏代谢，证明了这一现象。
