Xuan S Y, Yuan J W, Wang J, Guan X L, Ge L H, Shimono Y M
Stomatology Center of Peking University Hospital, Beijing 100871, China.
Department of Pediatric Dentistry, Peking University School and Hospital of Stomatology & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.
Zhonghua Kou Qiang Yi Xue Za Zhi. 2017 Nov 9;52(11):667-671. doi: 10.3760/cma.j.issn.1002-0098.2017.11.004.
To evaluate the caries status of a cohort of 3-year-old caries-free children from 2 kindergartens in Beijing in a period of 2 years by using Cariostat caries activity test and to assess the sensitivity and specificity of Cariostat score as a caries risk indicator for caries-free children. Totally 426 3-year-old caries-free children from 2 kindergartens in Beijing were recruited in the present study. Informed consents were obtained from the children's parents. Dental plaque samples of the children were collected and the Cariostat caries activity tests were conducted at baseline and once a year for 2 years. After two years, the caries status of the cohort children were re-evaluated and the caries incidences amongst children with high (2.0, 2.5, 3.0), medium (1.5) and low (1.0, 0.5, 0.0) levels of Cariostat scores were compared and analyzed. Totally 864 3-year-old children from 2 kindergartens were screened before the study startedand 426 (49.3%) children were caries free. After 2-year follow-up, 312 out of 426 (73.2%) remained in the study. The overall caries incident rate was 46.5% (145/312). The caries incident rate of children with high level of Cariostat scores was 88.9% (88/99), while the caries incident rates of children with medium and low levels of Cariostat scores was 38.7% (36/93) and 17.5% (21/120), respectively. The sensitivity and specificity of the Cariostat test in assessing the caries risk of 3-year-old caries-free children in a period of 2 years were 60.7% and 93.4%, respectively. Cariostat caries activity test can be used as an indicator to predict the caries risk of 3-year-old caries-free children. Comprehensive caries management could be conducted for children in kindergartens based on the caries risk assessment results of caries experience and the Cariostat score.
采用Cariostat龋活性试验评估北京2所幼儿园3岁无龋儿童队列2年内的龋病状况，并评估Cariostat评分作为无龋儿童龋病风险指标的敏感性和特异性。本研究共纳入北京2所幼儿园的426名3岁无龋儿童。获得了儿童家长的知情同意书。在基线时以及之后2年每年收集儿童的牙菌斑样本并进行Cariostat龋活性试验。2年后，对该队列儿童的龋病状况进行重新评估，并比较和分析Cariostat评分高（2.0、2.5、3.0）、中（1.5）和低（1.0、0.5、0.0）水平儿童的龋病发病率。在研究开始前，对2所幼儿园的864名3岁儿童进行了筛查，其中426名（49.3%）儿童无龋。经过2年随访，426名儿童中有312名（73.2%）仍在研究中。总体龋病发病率为46.5%（145/312）。Cariostat评分高的儿童龋病发病率为88.9%（88/99），而Cariostat评分中等和低的儿童龋病发病率分别为38.7%（36/93）和17.5%（21/120）。Cariostat试验在评估3岁无龋儿童2年内龋病风险的敏感性和特异性分别为60.7%和93.4%。Cariostat龋活性试验可作为预测3岁无龋儿童龋病风险的指标。可根据龋病经验和Cariostat评分的龋病风险评估结果，对幼儿园儿童进行综合龋病管理。
